ID: ALA3734145
Type: Binding
Description: Inhibition of PFKFB3/PFKFB4 in human Panc1 cells assessed as fructose -2,6-bisphosphate production preincubated for 1 hr followed by addition of D-glucose measured after 2 hrs by spectrophotometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PANC-1
Target: fructose-2,6-bisphosphatase 3/4(ALA3832646)
Document: ALA3727345
Inhibition of PFKFB3/PFKFB4 in human Panc1 cells assessed as fructose -2,6-bisphosphate production preincubated for 1 hr followed by addition of D-glucose measured after 2 hrs by spectrophotometry: 38
Bioactivity
Activity Types for Assay ALA3734145
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
389.50 | 4.83 | 4.83 |
413.48 | 3.40 | 3.40 |
397.49 | 3.70 | 3.70 |
381.86 | 4.36 | 4.36 |
395.89 | 4.45 | 4.45 |
394.50 | 3.77 | 3.77 |
403.53 | 4.92 | 4.92 |
423.94 | 5.23 | 5.23 |
413.53 | 4.31 | 4.31 |
423.94 | 5.23 | 5.23 |
451.95 | 4.61 | 4.61 |
467.01 | 4.77 | 4.77 |
485.59 | 3.96 | 3.96 |
440.34 | 4.56 | 4.56 |
391.47 | 3.81 | 3.81 |
395.89 | 4.45 | 4.45 |