Basic Information
ID: ALA3734146
Type: Binding
Description: Inhibition of PFKFB3/PFKFB4 in human MCF7 cells assessed as fructose -2,6-bisphosphate production preincubated for 1 hr followed by addition of D-glucose measured after 2 hrs by spectrophotometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MCF7
Target: fructose-2,6-bisphosphatase 3/4(ALA3832646)
Document: ALA3727345
Inhibition of PFKFB3/PFKFB4 in human MCF7 cells assessed as fructose -2,6-bisphosphate production preincubated for 1 hr followed by addition of D-glucose measured after 2 hrs by spectrophotometry: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3734146
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.89 | 4.16 | 4.16 |
| 404.90 | 5.32 | 5.32 |