Basic Information
ID: ALA3734148
Type: Binding
Description: Inhibition of PFKFB3/PFKFB4 in human Panc1 cells assessed as fructose -2,6-bisphosphate production at 12.5 uM preincubated for 1 hr followed by addition of D-glucose measured after 2 hrs by spectrophotometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PANC-1
Target: fructose-2,6-bisphosphatase 3/4(ALA3832646)
Document: ALA3727345
Inhibition of PFKFB3/PFKFB4 in human Panc1 cells assessed as fructose -2,6-bisphosphate production at 12.5 uM preincubated for 1 hr followed by addition of D-glucose measured after 2 hrs by spectrophotometry: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3734148
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.99 | 5.32 | 5.32 |
| 409.92 | 4.84 | 4.84 |
| 439.94 | 4.47 | 4.47 |
| 471.99 | 6.02 | 6.02 |
| 452.00 | 6.01 | 6.01 |
| 457.96 | 5.88 | 5.88 |
| 465.98 | 4.86 | 4.86 |
| 387.46 | 4.45 | 4.45 |
| 430.96 | 4.61 | 4.61 |
| 478.95 | 5.09 | 5.09 |