Basic Information
ID: ALA3734165
Type: Binding
Description: Inhibition of recombinant full-length human PKC-iota expressed in Sf21 cells using FAM-PKCs pseudopeptide derived peptide substrate and 150 uM ATP by fluorescence polarization based IMAP assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: Protein kinase C iota(ALA2598)
Document: ALA3727368
Inhibition of recombinant full-length human PKC-iota expressed in Sf21 cells using FAM-PKCs pseudopeptide derived peptide substrate and 150 uM ATP by fluorescence polarization based IMAP assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3734165
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.54 | 3.32 | 3.32 |
| 383.48 | 2.36 | 2.36 |
| 353.50 | 3.64 | 3.64 |
| 343.48 | 2.91 | 2.91 |
| 327.41 | 2.20 | 2.20 |
| 429.59 | 4.92 | 4.92 |
| 445.59 | 4.62 | 4.62 |
| 429.59 | 4.92 | 4.92 |
| 445.59 | 4.62 | 4.62 |
| 433.56 | 4.75 | 4.75 |
| 433.56 | 4.75 | 4.75 |
| 465.63 | 5.77 | 5.77 |
| 429.59 | 4.92 | 4.92 |
| 445.59 | 4.62 | 4.62 |
| 431.57 | 4.32 | 4.32 |
| 416.55 | 4.01 | 4.01 |
| 416.55 | 4.01 | 4.01 |
| 416.55 | 4.01 | 4.01 |
| 422.58 | 4.07 | 4.07 |
| 395.58 | 4.81 | 4.81 |
| 471.66 | 5.83 | 5.83 |
| 379.53 | 4.19 | 4.19 |
| 454.60 | 5.10 | 5.10 |
| 463.63 | 4.53 | 4.53 |
| 431.57 | 4.32 | 4.32 |
| 431.57 | 4.32 | 4.32 |
| 429.59 | 5.00 | 5.00 |
| 520.66 | 4.93 | 4.93 |
| 520.66 | 4.93 | 4.93 |
| 443.62 | 5.25 | 5.25 |
| 473.60 | 3.97 | 3.97 |
| 473.60 | 3.97 | 3.97 |
| 433.61 | 4.52 | 4.52 |
| 433.61 | 4.52 | 4.52 |
| 417.54 | 3.81 | 3.81 |
| 417.54 | 3.81 | 3.81 |
| 516.67 | 5.03 | 5.03 |
| 440.57 | 3.81 | 3.81 |
| 433.56 | 4.75 | 4.75 |
| 445.59 | 4.62 | 4.62 |
| 431.57 | 4.32 | 4.32 |
| 426.55 | 3.42 | 3.42 |
| 368.47 | 2.03 | 2.03 |
| 382.49 | 2.42 | 2.42 |
| 396.52 | 2.66 | 2.66 |
| 394.50 | 2.42 | 2.42 |
| 408.53 | 2.81 | 2.81 |
| 410.55 | 3.20 | 3.20 |
| 411.54 | 1.57 | 1.57 |
| 354.48 | 2.50 | 2.50 |
| 340.46 | 2.11 | 2.11 |
| 382.54 | 3.14 | 3.14 |
| 352.46 | 3.37 | 3.37 |
| 331.83 | 3.18 | 3.18 |
| 395.92 | 4.39 | 4.39 |
| 417.58 | 5.03 | 5.03 |
| 389.53 | 4.35 | 4.35 |
| 516.47 | 6.16 | 6.16 |
| 516.47 | 6.16 | 6.16 |
| 390.31 | 3.60 | 3.60 |
| 454.40 | 4.81 | 4.81 |
| 378.30 | 3.58 | 3.58 |
| 378.30 | 3.58 | 3.58 |
| 390.31 | 3.60 | 3.60 |
| 406.35 | 4.18 | 4.18 |
| 496.48 | 5.80 | 5.80 |
| 496.48 | 5.80 | 5.80 |
| 440.37 | 4.50 | 4.50 |
| 454.40 | 4.81 | 4.81 |
| 364.23 | 2.41 | 2.41 |
| 378.30 | 3.49 | 3.49 |
| 390.31 | 3.60 | 3.60 |
| 390.31 | 3.68 | 3.68 |
| 390.31 | 3.68 | 3.68 |
| 390.31 | 3.68 | 3.68 |
| 376.28 | 3.29 | 3.29 |
| 364.27 | 3.15 | 3.15 |
| 406.35 | 4.30 | 4.30 |
| 392.33 | 3.91 | 3.91 |
| 446.42 | 5.23 | 5.23 |
| 350.25 | 2.89 | 2.89 |
| 376.28 | 2.93 | 2.93 |
| 376.28 | 3.29 | 3.29 |
| 394.27 | 3.43 | 3.43 |
| 303.37 | 2.65 | 2.65 |
| 315.38 | 2.67 | 2.67 |
| 379.46 | 3.87 | 3.87 |
| 429.59 | 5.13 | 5.13 |
| 441.56 | 4.43 | 4.43 |
| 377.48 | 3.23 | 3.23 |
| 427.54 | 4.13 | 4.13 |
| 441.56 | 4.14 | 4.14 |
| 456.58 | 5.01 | 5.01 |
| 427.54 | 4.13 | 4.13 |
| 483.65 | 5.25 | 5.25 |
| 457.63 | 5.77 | 5.77 |
| 457.63 | 5.77 | 5.77 |
| 426.55 | 4.73 | 4.73 |
| 426.55 | 4.73 | 4.73 |
| 499.76 |