Basic Information
ID: ALA3734210
Type: Functional
Description: Antagonist activity against human GPR10 receptor expressed in HEK293 cells assessed as inhibition of PrRP-induced intracellular calcium mobilization pre-incubated for 15 mins before PrRP addition by Fluo-8 dye based fluorescence imaging plate reader method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3734210
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 559.95 | 4.28 | 4.28 |
| 551.40 | 4.92 | 4.92 |
| 481.38 | 4.55 | 4.55 |
| 564.97 | 3.84 | 3.84 |
| 556.42 | 4.48 | 4.48 |
| 522.86 | 4.12 | 4.12 |
| 473.36 | 3.98 | 3.98 |
| 543.37 | 4.35 | 4.35 |
| 551.93 | 3.70 | 3.70 |
| 556.46 | 4.59 | 4.59 |
| 520.94 | 4.74 | 4.74 |
| 511.50 | 3.95 | 3.95 |
| 529.49 | 4.09 | 4.09 |
| 553.54 | 4.74 | 4.74 |
| 543.57 | 4.69 | 4.69 |
| 536.56 | 4.24 | 4.24 |
| 554.55 | 4.38 | 4.38 |
| 497.48 | 3.56 | 3.56 |
| 536.94 | 4.11 | 4.11 |
| 553.01 | 4.82 | 4.82 |
| 534.97 | 4.66 | 4.66 |
| 532.95 | 4.75 | 4.75 |
| 520.94 | 4.65 | 4.65 |
| 633.50 | 4.84 | 4.84 |
| 546.93 | 5.09 | 5.09 |
| 492.52 | 4.06 | 4.06 |
| 512.94 | 4.41 | 4.41 |
| 573.98 | 4.67 | 4.67 |
| 555.99 | 4.53 | 4.53 |
| 565.42 | 5.31 | 5.31 |
| 598.03 | 5.31 | 5.31 |
| 571.00 | 4.30 | 4.30 |
| 600.04 | 4.54 | 4.54 |
| 618.49 | 5.21 | 5.21 |
| 523.52 | 4.24 | 4.24 |
| 533.51 | 3.10 | 3.10 |
| 523.85 | 4.37 | 4.37 |
| 503.39 | 3.75 | 3.75 |
| 516.43 | 3.88 | 3.88 |
| 589.02 | 3.47 | 3.47 |
| 519.53 | 4.53 | 4.53 |
| 537.52 | 4.67 | 4.67 |
| 501.41 | 4.62 | 4.62 |
| 545.57 | 5.21 | 5.21 |
| 545.57 | 5.21 | 5.21 |
| 516.52 | 4.09 | 4.09 |
| 500.52 | 4.31 | 4.31 |
| 607.01 | 3.61 | 3.61 |
| 575.94 | 4.25 | 4.25 |