Basic Information
ID: ALA3734215
Type: Functional
Description: Antagonist activity against human CCR10 expressed in human KJMGER8 cells assessed as inhibition of human recombinant CTACK-induced increase in intracellular calcium level at 100 nmol/L pre-incubated for 30 mins before human recombinant CTACK stimulation for 5 mins by FLIPR assay
Organism: Homo sapiens
Cell type: KJMGER8
Activity Charts
Bioactivity
Activity Types for Assay ALA3734215
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 576.65 | 4.16 | 4.16 |
| 536.63 | 4.24 | 4.24 |
| 554.62 | 4.38 | 4.38 |
| 608.59 | 4.92 | 4.92 |
| 566.63 | 4.52 | 4.52 |
| 579.08 | 4.36 | 4.36 |
| 582.09 | 4.15 | 4.15 |
| 569.04 | 4.19 | 4.19 |
| 597.07 | 4.50 | 4.50 |
| 600.08 | 4.29 | 4.29 |
| 587.08 | 4.21 | 4.21 |
| 583.09 | 5.03 | 5.03 |
| 599.09 | 4.81 | 4.81 |
| 614.10 | 4.60 | 4.60 |
| 571.08 | 4.89 | 4.89 |
| 571.08 | 4.89 | 4.89 |
| 550.62 | 3.77 | 3.77 |
| 599.09 | 4.81 | 4.81 |
| 619.51 | 5.15 | 5.15 |
| 634.52 | 4.95 | 4.95 |
| 630.08 | 4.57 | 4.57 |
| 619.51 | 5.15 | 5.15 |
| 634.52 | 4.95 | 4.95 |
| 605.48 | 4.76 | 4.76 |
| 661.54 | 4.78 | 4.78 |
| 591.45 | 4.37 | 4.37 |
| 593.47 | 4.78 | 4.78 |
| 607.50 | 5.17 | 5.17 |
| 653.06 | 5.52 | 5.52 |
| 618.07 | 4.43 | 4.43 |
| 582.63 | 4.29 | 4.29 |
| 609.66 | 4.23 | 4.23 |
| 589.02 | 4.25 | 4.25 |
| 618.07 | 4.43 | 4.43 |
| 572.57 | 3.73 | 3.73 |
| 586.60 | 4.12 | 4.12 |
| 662.09 | 4.99 | 4.99 |
| 605.48 | 4.76 | 4.76 |
| 634.52 | 4.95 | 4.95 |
| 617.08 | 4.95 | 4.95 |
| 629.09 | 4.95 | 4.95 |
| 632.09 | 4.74 | 4.74 |
| 607.67 | 3.59 | 3.59 |
| 624.12 | 4.10 | 4.10 |
| 581.10 | 4.39 | 4.39 |
| 621.12 | 4.31 | 4.31 |
| 624.12 | 4.10 | 4.10 |
| 592.65 | 3.80 | 3.80 |
| 607.67 | 3.59 | 3.59 |
| 613.07 | 4.14 | 4.14 |
| 592.65 | 3.80 | 3.80 |
| 604.66 | 3.80 | 3.80 |
| 629.53 | 4.66 | 4.66 |
| 641.54 | 4.66 | 4.66 |
| 595.08 | 3.92 | 3.92 |
| 609.11 | 4.31 | 4.31 |
| 621.12 | 4.31 | 4.31 |
| 651.14 | 3.94 | 3.94 |
| 655.66 | 3.98 | 3.98 |
| 612.09 | 3.75 | 3.75 |
| 627.10 | 3.54 | 3.54 |
| 564.69 | 4.97 | 4.97 |
| 579.66 | 2.96 | 2.96 |
| 580.64 | 3.39 | 3.39 |
| 566.62 | 2.74 | 2.74 |
| 579.66 | 3.95 | 3.95 |
| 627.70 | 5.45 | 5.45 |
| 621.70 | 3.67 | 3.67 |
| 595.73 | 4.11 | 4.11 |
| 604.59 | 4.31 | 4.31 |
| 586.67 | 3.18 | 3.18 |
| 566.62 | 3.98 | 3.98 |
| 563.66 | 4.22 | 4.22 |
| 562.65 | 4.15 | 4.15 |
| 558.66 | 3.58 | 3.58 |
| 561.67 | 3.37 | 3.37 |
| 586.05 | 3.95 | 3.95 |
| 647.55 | 5.59 | 5.59 |
| 641.52 | 5.53 | 5.53 |
| 641.52 | 5.53 | 5.53 |
| 680.19 | 4.26 | 4.26 |
| 678.09 | 4.65 | 4.65 |