Basic Information
ID: ALA3734252
Type: Binding
Description: Binding affinity to pyruvate dehydrogenase kinase 1 (unknown origin) incubated for 90 mins by VER-00160364 probe based fluorescence polarization assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Pyruvate dehydrogenase kinase isoform 1(ALA4766)
Document: ALA3727364
Binding affinity to pyruvate dehydrogenase kinase 1 (unknown origin) incubated for 90 mins by VER-00160364 probe based fluorescence polarization assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3734252
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 523.61 | 5.83 | 5.83 |
| 523.61 | 5.83 | 5.83 |
| 478.60 | 5.34 | 5.34 |
| 525.63 | 5.77 | 5.77 |
| 523.61 | 5.83 | 5.83 |
| 523.61 | 5.83 | 5.83 |
| 523.61 | 5.83 | 5.83 |
| 556.56 | 6.18 | 6.18 |
| 524.60 | 5.22 | 5.22 |
| 502.59 | 5.29 | 5.29 |
| 396.47 | 3.71 | 3.71 |
| 522.63 | 6.43 | 6.43 |
| 522.63 | 6.43 | 6.43 |
| 537.04 | 5.94 | 5.94 |
| 410.50 | 4.02 | 4.02 |
| 538.63 | 5.53 | 5.53 |
| 516.62 | 5.60 | 5.60 |
| 585.71 | 5.86 | 5.86 |
| 563.70 | 5.55 | 5.55 |
| 566.71 | 4.22 | 4.22 |
| 578.72 | 4.31 | 4.31 |
| 565.67 | 4.40 | 4.40 |
| 553.66 | 3.99 | 3.99 |
| 606.73 | 4.23 | 4.23 |
| 599.68 | 5.80 | 5.80 |
| 571.63 | 5.02 | 5.02 |
| 586.70 | 5.25 | 5.25 |
| 451.94 | 5.43 | 5.43 |
| 446.53 | 4.90 | 4.90 |
| 467.55 | 5.92 | 5.92 |
| 487.61 | 6.29 | 6.29 |
| 452.54 | 6.22 | 6.22 |
| 453.52 | 5.62 | 5.62 |
| 470.47 | 6.09 | 6.09 |
| 459.55 | 5.68 | 5.68 |
| 493.97 | 5.19 | 5.19 |
| 462.53 | 5.09 | 5.09 |
| 433.49 | 4.47 | 4.47 |
| 538.47 | 7.11 | 7.11 |
| 499.51 | 6.10 | 6.10 |
| 418.48 | 4.05 | 4.05 |
| 461.93 | 5.59 | 5.59 |
| 482.56 | 5.71 | 5.71 |
| 467.93 | 5.13 | 5.13 |
| 480.59 | 6.78 | 6.78 |
| 496.59 | 6.54 | 6.54 |
| 432.50 | 4.56 | 4.56 |
| 484.55 | 6.67 | 6.67 |
| 476.95 | 5.60 | 5.60 |
| 510.62 | 6.93 | 6.93 |
| 488.59 | 5.67 | 5.67 |
| 473.58 | 5.99 | 5.99 |
| 501.01 | 7.18 | 7.18 |
| 521.52 | 6.64 | 6.64 |
| 517.01 | 6.88 | 6.88 |
| 466.56 | 6.53 | 6.53 |
| 484.55 | 6.67 | 6.67 |
| 511.56 | 5.40 | 5.40 |
| 431.52 | 5.08 | 5.08 |
| 486.38 | 6.08 | 6.08 |
| 471.51 | 5.76 | 5.76 |
| 417.49 | 4.77 | 4.77 |
| 431.52 | 5.03 | 5.03 |
| 487.97 | 6.27 | 6.27 |
| 495.58 | 4.02 | 4.02 |
| 461.52 | 5.86 | 5.86 |
| 445.91 | 5.36 | 5.36 |
| 411.46 | 4.71 | 4.71 |
| 412.45 | 4.11 | 4.11 |
| 431.52 | 5.08 | 5.08 |
| 446.89 | 4.76 | 4.76 |
| 488.93 | 4.52 | 4.52 |
| 494.47 | 5.43 | 5.43 |
| 471.90 | 4.93 | 4.93 |
| 469.55 | 4.48 | 4.48 |
| 481.34 | 5.41 | 5.41 |
| 533.43 | 6.44 | 6.44 |
| 468.54 | 5.32 | 5.32 |
| 437.46 | 5.15 | 5.15 |
| 440.50 | 4.67 | 4.67 |
| 413.44 | 3.38 | 3.38 |
| 428.45 | 3.81 | 3.81 |
| 478.96 | 5.17 | 5.17 |
| 453.52 | 5.62 | 5.62 |
| 456.89 | 4.93 | 4.93 |
| 457.49 | 4.42 | 4.42 |
| 446.89 | 4.76 | 4.76 |
| 446.89 | 4.76 | 4.76 |
| 498.54 | 4.59 | 4.59 |
| 437.46 | 5.15 | 5.15 |
| 440.50 | 4.75 | 4.75 |
| 462.89 | 4.46 | 4.46 |
| 441.49 | 4.23 | 4.23 |
| 412.45 | 4.11 | 4.11 |
| 448.48 | 4.95 | 4.95 |
| 427.46 | 3.84 | 3.84 |
| 484.58 | 5.01 | 5.01 |
| 462.51 | 5.26 | 5.26 |
| 465.43 | 5.42 | 5.42 |
| 475.55 | 6.12 | 6.12 |