Basic Information
ID: ALA3734253
Type: Binding
Description: Inhibition of pyruvate dehydrogenase kinase 1 (unknown origin) assessed as reduction in E1alpha phosphorylation incubated for 1 hr by DELFIA method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3734253
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 626.16 | 5.18 | 5.18 |
| 598.15 | 5.26 | 5.26 |
| 611.17 | 6.87 | 6.87 |
| 605.14 | 6.81 | 6.81 |
| 515.01 | 4.97 | 4.97 |
| 585.10 | 5.35 | 5.35 |
| 606.12 | 6.20 | 6.20 |
| 606.12 | 6.20 | 6.20 |
| 626.18 | 6.57 | 6.57 |
| 620.15 | 6.51 | 6.51 |
| 621.14 | 5.90 | 5.90 |
| 472.57 | 5.94 | 5.94 |
| 535.65 | 7.35 | 7.35 |
| 445.54 | 5.33 | 5.33 |
| 502.38 | 5.78 | 5.78 |
| 572.91 | 7.76 | 7.76 |
| 511.39 | 6.25 | 6.25 |
| 479.99 | 5.99 | 5.99 |
| 497.34 | 5.11 | 5.11 |
| 426.48 | 4.29 | 4.29 |
| 488.96 | 5.66 | 5.66 |
| 447.49 | 5.56 | 5.56 |
| 426.48 | 4.29 | 4.29 |
| 481.34 | 5.41 | 5.41 |
| 444.92 | 5.97 | 5.97 |
| 505.00 | 5.24 | 5.24 |
| 505.00 | 5.24 | 5.24 |
| 404.47 | 3.96 | 3.96 |
| 586.57 | 6.18 | 6.18 |
| 510.59 | 5.53 | 5.53 |
| 564.56 | 6.24 | 6.24 |
| 532.60 | 5.47 | 5.47 |
| 467.55 | 5.92 | 5.92 |
| 460.53 | 6.47 | 6.47 |
| 478.52 | 6.61 | 6.61 |
| 459.93 | 5.92 | 5.92 |
| 480.35 | 6.02 | 6.02 |
| 552.97 | 5.24 | 5.24 |
| 516.99 | 5.00 | 5.00 |
| 570.96 | 5.54 | 5.54 |
| 545.04 | 5.64 | 5.64 |
| 569.02 | 5.89 | 5.89 |
| 543.02 | 5.39 | 5.39 |
| 570.01 | 5.28 | 5.28 |
| 560.05 | 4.54 | 4.54 |
| 584.98 | 5.93 | 5.93 |
| 572.06 | 5.67 | 5.67 |
| 588.06 | 4.91 | 4.91 |
| 601.11 | 4.82 | 4.82 |
| 557.05 | 5.78 | 5.78 |
| 571.08 | 6.17 | 6.17 |
| 680.16 | 6.29 | 6.29 |
| 579.06 | 6.29 | 6.29 |
| 585.09 | 6.36 | 6.36 |
| 559.07 | 6.03 | 6.03 |
| 650.14 | 5.75 | 5.75 |
| 546.03 | 4.20 | 4.20 |
| 572.07 | 4.73 | 4.73 |
| 573.09 | 6.42 | 6.42 |
| 532.98 | 3.97 | 3.97 |
| 547.01 | 4.63 | 4.63 |
| 573.05 | 5.16 | 5.16 |
| 565.02 | 6.20 | 6.20 |
| 543.67 | 7.06 | 7.06 |
| 543.07 | 6.27 | 6.27 |
| 563.49 | 6.61 | 6.61 |
| 597.04 | 6.89 | 6.89 |
| 531.01 | 4.54 | 4.54 |
| 545.04 | 4.93 | 4.93 |
| 559.07 | 5.58 | 5.58 |
| 545.04 | 4.93 | 4.93 |
| 543.07 | 6.35 | 6.35 |
| 550.99 | 5.81 | 5.81 |
| 547.01 | 4.93 | 4.93 |
| 615.13 | 6.33 | 6.33 |
| 554.05 | 6.13 | 6.13 |
| 529.04 | 5.96 | 5.96 |
| 543.67 | 7.06 | 7.06 |
| 543.07 | 6.35 | 6.35 |
| 545.04 | 5.20 | 5.20 |
| 508.62 | 5.61 | 5.61 |
| 575.68 | 7.59 | 7.59 |
| 577.66 | 6.44 | 6.44 |
| 558.08 | 5.11 | 5.11 |
| 565.02 | 6.20 | 6.20 |
| 531.06 | 6.21 | 6.21 |
| 503.00 | 5.43 | 5.43 |
| 579.48 | 5.85 | 5.85 |
| 563.49 | 6.61 | 6.61 |
| 577.51 | 7.00 | 7.00 |
| 503.00 | 5.47 | 5.47 |
| 559.07 | 5.84 | 5.84 |
| 547.06 | 5.69 | 5.69 |
| 575.07 | 5.07 | 5.07 |
| 603.12 | 5.85 | 5.85 |
| 533.03 | 5.30 | 5.30 |
| 575.71 | 7.19 | 7.19 |
| 554.65 | 4.73 | 4.73 |
| 573.69 | 6.94 | 6.94 |
| 540.66 | 5.74 | 5.74 |
| 589.69 | 6.18 | 6.18 |
| 592.72 | 5.31 | 5.31 |
| 452.92 | 4.82 | 4.82 |
| 468.92 | 4.52 | 4.52 |
| 467.55 | 5.92 | 5.92 |