Basic Information
ID: ALA3734517
Type: Functional
Description: Antagonist activity against rat/human CRFR1 expressed in CHO cells assessed as inhibition of rat/human CRF-induced cAMP accumulation pre-incubated for 15 mins before CRF stimulation for 30 mins by FRET based HTRF assay
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3734517
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.33 | 5.89 | 5.89 |
| 521.31 | 6.44 | 6.44 |
| 517.35 | 6.53 | 6.53 |
| 426.95 | 4.05 | 4.05 |
| 451.88 | 4.63 | 4.63 |
| 427.94 | 3.56 | 3.56 |
| 427.94 | 3.39 | 3.39 |
| 494.92 | 5.86 | 5.86 |
| 459.51 | 5.02 | 5.02 |
| 508.97 | 5.98 | 5.98 |
| 509.96 | 5.38 | 5.38 |
| 482.91 | 5.88 | 5.88 |
| 485.33 | 5.89 | 5.89 |
| 496.93 | 6.11 | 6.11 |
| 466.89 | 4.40 | 4.40 |
| 451.88 | 4.99 | 4.99 |
| 465.90 | 5.00 | 5.00 |
| 546.37 | 4.64 | 4.64 |
| 445.39 | 5.61 | 5.61 |
| 425.96 | 4.66 | 4.66 |
| 441.93 | 4.55 | 4.55 |
| 460.41 | 5.31 | 5.31 |
| 508.97 | 5.98 | 5.98 |
| 429.92 | 4.56 | 4.56 |
| 492.97 | 6.28 | 6.28 |
| 468.33 | 5.12 | 5.12 |
| 439.99 | 4.96 | 4.96 |
| 455.99 | 4.67 | 4.67 |
| 460.41 | 5.31 | 5.31 |
| 464.37 | 5.22 | 5.22 |
| 426.95 | 4.17 | 4.17 |
| 455.00 | 4.80 | 4.80 |
| 412.92 | 3.69 | 3.69 |
| 457.98 | 5.18 | 5.18 |
| 468.88 | 5.38 | 5.38 |
| 479.93 | 5.48 | 5.48 |