Basic Information
ID: ALA3734546
Type: Binding
Description: Inhibition of STIM1/Orai1 in rat RBL2H3 cells assessed as inhibition of upslope incubated for 5 mins followed by thapsigargin addition for 25 mins measured for 7 secs by fluo4-AM dye-based FLIPR assay
Organism: Rattus norvegicus
Cell type: RBL-2H3
Activity Charts
Bioactivity
Activity Types for Assay ALA3734546
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.29 | 6.42 | 6.42 |
| 386.84 | 5.91 | 5.91 |
| 404.83 | 6.05 | 6.05 |
| 386.45 | 5.86 | 5.86 |
| 368.46 | 5.72 | 5.72 |
| 384.91 | 6.24 | 6.24 |
| 406.87 | 6.21 | 6.21 |
| 405.33 | 6.58 | 6.58 |
| 388.88 | 6.07 | 6.07 |
| 384.41 | 5.70 | 5.70 |
| 366.42 | 5.56 | 5.56 |
| 365.43 | 5.00 | 5.00 |
| 365.43 | 5.00 | 5.00 |
| 381.89 | 5.52 | 5.52 |
| 383.42 | 5.14 | 5.14 |
| 401.40 | 4.04 | 4.04 |
| 383.41 | 3.90 | 3.90 |
| 400.85 | 3.81 | 3.81 |
| 404.28 | 5.82 | 5.82 |
| 387.44 | 5.26 | 5.26 |
| 407.85 | 5.60 | 5.60 |
| 367.86 | 5.21 | 5.21 |
| 367.86 | 5.21 | 5.21 |
| 400.81 | 4.95 | 4.95 |
| 414.84 | 5.51 | 5.51 |
| 366.37 | 4.12 | 4.12 |
| 386.79 | 4.47 | 4.47 |
| 388.32 | 4.09 | 4.09 |
| 386.79 | 4.47 | 4.47 |
| 402.35 | 4.28 | 4.28 |
| 414.34 | 4.47 | 4.47 |
| 430.80 | 4.98 | 4.98 |
| 384.36 | 4.14 | 4.14 |
| 400.81 | 4.66 | 4.66 |
| 413.42 | 5.49 | 5.49 |
| 414.41 | 4.88 | 4.88 |
| 396.42 | 4.74 | 4.74 |
| 396.42 | 4.74 | 4.74 |
| 430.87 | 5.39 | 5.39 |
| 395.43 | 5.35 | 5.35 |
| 411.89 | 5.86 | 5.86 |
| 395.43 | 5.35 | 5.35 |
| 396.42 | 4.74 | 4.74 |
| 378.43 | 4.60 | 4.60 |
| 378.43 | 4.60 | 4.60 |
| 412.88 | 5.26 | 5.26 |
| 377.44 | 5.21 | 5.21 |
| 393.90 | 5.72 | 5.72 |
| 402.45 | 4.80 | 4.80 |
| 403.44 | 4.20 | 4.20 |
| 385.45 | 4.06 | 4.06 |
| 385.45 | 4.06 | 4.06 |
| 419.89 | 4.71 | 4.71 |
| 384.46 | 4.66 | 4.66 |
| 400.92 | 5.18 | 5.18 |
| 385.40 | 4.94 | 4.94 |
| 386.38 | 4.33 | 4.33 |
| 368.39 | 4.20 | 4.20 |
| 368.39 | 4.20 | 4.20 |
| 402.84 | 4.85 | 4.85 |
| 367.41 | 4.80 | 4.80 |
| 383.86 | 5.31 | 5.31 |
| 401.46 | 5.41 | 5.41 |
| 383.47 | 5.27 | 5.27 |
| 399.93 | 5.78 | 5.78 |
| 414.41 | 4.88 | 4.88 |
| 396.42 | 4.74 | 4.74 |
| 412.88 | 5.26 | 5.26 |
| 378.43 | 4.60 | 4.60 |
| 394.89 | 5.12 | 5.12 |
| 369.34 | 4.56 | 4.56 |
| 370.33 | 3.95 | 3.95 |
| 386.79 | 4.47 | 4.47 |
| 387.33 | 4.70 | 4.70 |
| 370.33 | 3.95 | 3.95 |
| 371.32 | 3.35 | 3.35 |
| 388.32 | 4.09 | 4.09 |
| 389.31 | 3.49 | 3.49 |
| 391.37 | 5.44 | 5.44 |
| 409.36 | 5.58 | 5.58 |
| 411.34 | 4.37 | 4.37 |
| 393.35 | 4.23 | 4.23 |
| 410.35 | 4.97 | 4.97 |
| 392.36 | 4.83 | 4.83 |