Basic Information
ID: ALA3734552
Type: Functional
Description: Agonist activity at human recombinant ALX receptor expressed in HEK293 cells co-expressing G-protein Galpha16 assessed as effect on calcium response by Fluo-4-AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3734552
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.34 | 2.94 | 2.94 |
| 471.40 | 3.84 | 3.84 |
| 476.46 | 4.29 | 4.29 |
| 474.44 | 4.04 | 4.04 |
| 503.49 | 3.19 | 3.19 |
| 458.40 | 3.33 | 3.33 |
| 430.35 | 2.69 | 2.69 |
| 446.39 | 3.32 | 3.32 |
| 488.47 | 4.45 | 4.45 |
| 419.32 | 2.71 | 2.71 |
| 432.32 | 2.21 | 2.21 |
| 530.46 | 4.34 | 4.34 |
| 429.36 | 4.27 | 4.27 |
| 418.34 | 2.68 | 2.68 |
| 447.37 | 3.76 | 3.76 |
| 444.37 | 3.08 | 3.08 |
| 443.26 | 3.89 | 3.89 |
| 407.28 | 3.30 | 3.30 |
| 418.34 | 2.55 | 2.55 |
| 445.36 | 3.51 | 3.51 |
| 473.41 | 3.88 | 3.88 |
| 449.41 | 4.09 | 4.09 |
| 502.50 | 4.84 | 4.84 |
| 444.37 | 3.08 | 3.08 |
| 504.43 | 3.86 | 3.86 |
| 462.39 | 2.30 | 2.30 |
| 473.37 | 2.36 | 2.36 |
| 472.43 | 3.82 | 3.82 |
| 419.32 | 2.98 | 2.98 |
| 519.44 | 4.84 | 4.84 |
| 472.43 | 3.82 | 3.82 |
| 405.29 | 2.32 | 2.32 |
| 477.40 | 3.34 | 3.34 |
| 400.28 | 2.86 | 2.86 |
| 469.38 | 3.62 | 3.62 |
| 480.41 | 3.99 | 3.99 |
| 488.47 | 4.41 | 4.41 |
| 469.38 | 3.62 | 3.62 |
| 461.36 | 2.75 | 2.75 |
| 433.35 | 3.10 | 3.10 |
| 501.47 | 2.97 | 2.97 |
| 404.31 | 2.29 | 2.29 |
| 446.39 | 3.24 | 3.24 |
| 532.48 | 4.64 | 4.64 |
| 518.45 | 4.20 | 4.20 |
| 458.40 | 3.43 | 3.43 |
| 456.34 | 2.62 | 2.62 |
| 441.33 | 4.13 | 4.13 |
| 474.44 | 4.06 | 4.06 |
| 446.39 | 3.28 | 3.28 |
| 433.35 | 3.37 | 3.37 |
| 472.43 | 3.82 | 3.82 |
| 470.37 | 3.01 | 3.01 |
| 544.49 | 4.73 | 4.73 |
| 518.45 | 4.25 | 4.25 |
| 431.37 | 4.38 | 4.38 |
| 461.40 | 3.74 | 3.74 |
| 447.33 | 2.90 | 2.90 |
| 544.47 | 3.22 | 3.22 |
| 497.44 | 4.10 | 4.10 |
| 483.41 | 3.91 | 3.91 |
| 432.32 | 2.21 | 2.21 |
| 460.42 | 3.67 | 3.67 |
| 431.37 | 4.52 | 4.52 |
| 546.51 | 5.03 | 5.03 |
| 514.51 | 4.84 | 4.84 |
| 466.38 | 3.97 | 3.97 |
| 546.51 | 4.88 | 4.88 |
| 503.40 | 5.04 | 5.04 |
| 401.30 | 3.49 | 3.49 |
| 417.35 | 4.13 | 4.13 |
| 445.40 | 4.91 | 4.91 |
| 497.44 | 4.10 | 4.10 |
| 550.50 | 4.41 | 4.41 |
| 474.44 | 4.06 | 4.06 |
| 544.49 | 4.73 | 4.73 |
| 474.40 | 2.66 | 2.66 |
| 486.41 | 3.38 | 3.38 |
| 500.44 | 3.73 | 3.73 |
| 534.50 | 5.00 | 5.00 |
| 459.43 | 5.25 | 5.25 |
| 445.40 | 4.77 | 4.77 |
| 458.40 | 3.43 | 3.43 |
| 488.43 | 3.05 | 3.05 |
| 483.41 | 4.00 | 4.00 |
| 503.44 | 4.45 | 4.45 |
| 580.52 | 5.29 | 5.29 |
| 457.41 | 4.86 | 4.86 |
| 558.52 | 4.98 | 4.98 |
| 443.39 | 4.66 | 4.66 |
| 544.49 | 4.73 | 4.73 |
| 508.42 | 3.43 | 3.43 |
| 488.43 | 3.49 | 3.49 |
| 580.52 | 5.56 | 5.56 |
| 516.44 | 3.95 | 3.95 |
| 572.54 | 5.37 | 5.37 |
| 509.44 | 4.59 | 4.59 |
| 532.44 | 5.50 | 5.50 |
| 434.33 | 2.43 | 2.43 |
| 435.36 | 3.59 | 3.59 |
| 447.37 | 3.74 | 3.74 |
| 475.39 | 2.58 | 2.58 |
| 403.32 | 3.72 | 3.72 |
| 446.39 | 3.46 | 3.46 |
| 486.45 | 4.21 | 4.21 |
| 444.37 | 3.08 | 3.08 |
| 417.35 | 3.99 | 3.99 |
| 432.36 | 3.07 | 3.07 |
| 432.36 | 2.89 | 2.89 |
| 480.41 | 3.99 | 3.99 |
| 485.43 | 4.14 | 4.14 |
| 488.47 | 4.43 | 4.43 |
| 487.44 | 3.60 | 3.60 |
| 437.58 | 3.45 | 3.45 |
| 442.99 | 3.49 | 3.49 |
| 464.64 | 4.06 | 4.06 |
| 500.48 | 3.89 | 3.89 |
| 487.44 | 3.60 | 3.60 |
| 493.47 | 3.66 | 3.66 |
| 422.57 | 3.15 | 3.15 |
| 401.60 | 3.11 | 3.11 |
| 435.61 | 3.43 | 3.43 |
| 417.55 | 1.49 | 1.49 |
| 427.63 | 3.50 | 3.50 |
| 427.63 | 3.50 | 3.50 |
| 429.61 | 2.68 | 2.68 |
| 459.57 | 2.81 | 2.81 |
| 449.02 | 3.56 | 3.56 |
| 439.59 | 2.77 | 2.77 |
| 411.55 | 2.72 | 2.72 |
| 514.51 | 4.45 | 4.45 |
| 491.55 | 4.34 | 4.34 |
| 451.61 | 3.00 | 3.00 |
| 401.60 | 2.97 | 2.97 |
| 387.57 | 2.72 | 2.72 |
| 425.57 | 3.02 | 3.02 |
| 478.66 | 4.36 | 4.36 |
| 435.61 | 3.17 | 3.17 |
| 415.58 | 2.29 | 2.29 |
| 439.60 | 2.21 | 2.21 |
| 443.98 | 2.89 | 2.89 |
| 500.48 | 3.89 | 3.89 |
| 464.64 | 4.06 | 4.06 |
| 454.62 | 3.73 | 3.73 |
| 478.66 | 4.36 | 4.36 |
| 446.60 | 3.93 | 3.93 |
| 482.63 | 4.19 | 4.19 |
| 415.62 | 3.36 | 3.36 |
| 525.12 | 5.22 | 5.22 |
| 449.56 | 2.98 | 2.98 |
| 470.68 | 4.20 | 4.20 |
| 491.66 | 3.96 | 3.96 |
| 499.08 | 4.71 | 4.71 |
| 502.70 | 4.28 | 4.28 |
| 489.66 | 3.05 | 3.05 |
| 474.65 | 3.58 | 3.58 |
| 465.64 | 3.17 | 3.17 |
| 497.44 | 4.24 | 4.24 |
| 518.41 | 5.30 | 5.30 |
| 500.44 | 3.73 | 3.73 |
| 499.84 | 5.23 | 5.23 |
| 433.35 | 3.37 | 3.37 |
| 474.40 | 3.20 | 3.20 |
| 498.25 | 4.92 | 4.92 |
| 475.38 | 3.68 | 3.68 |
| 431.37 | 4.52 | 4.52 |
| 500.46 | 4.65 | 4.65 |
| 517.43 | 4.83 | 4.83 |
| 446.35 | 2.60 | 2.60 |
| 466.38 | 4.35 | 4.35 |
| 417.35 | 3.99 | 3.99 |
| 486.45 | 4.06 | 4.06 |
| 480.41 | 4.36 | 4.36 |
| 447.37 | 3.71 | 3.71 |
| 503.80 | 5.44 | 5.44 |
| 486.45 | 4.21 | 4.21 |
| 469.38 | 3.69 | 3.69 |
| 443.39 | 4.52 | 4.52 |
| 486.44 | 4.34 | 4.34 |
| 432.36 | 2.89 | 2.89 |
| 513.86 | 5.57 | 5.57 |
| 483.41 | 4.03 | 4.03 |
| 429.36 | 4.13 | 4.13 |
| 533.47 | 4.85 | 4.85 |
| 518.46 | 5.45 | 5.45 |
| 417.35 | 4.13 | 4.13 |
| 497.41 | 5.10 | 5.10 |
| 477.40 | 5.05 | 5.05 |
| 503.83 | 4.34 | 4.34 |
| 470.64 | 2.78 | 2.78 |
| 449.60 | 3.65 | 3.65 |
| 428.60 | 3.21 | 3.21 |
| 469.65 | 3.39 | 3.39 |
| 453.58 | 2.92 | 2.92 |
| 455.60 | 3.14 | 3.14 |
| 477.57 | 4.69 | 4.69 |
| 454.57 | 2.31 | 2.31 |
| 483.41 | 3.91 | 3.91 |
| 547.48 | 3.73 | 3.73 |
| 468.64 | 3.31 | 3.31 |
| 506.51 | 3.95 | 3.95 |
| 518.47 | 4.03 | 4.03 |
| 460.37 | 2.81 | 2.81 |
| 492.37 | 2.60 | 2.60 |
| 486.41 | 3.34 | 3.34 |
| 418.29 | 1.82 | 1.82 |
| 529.52 | 3.75 | 3.75 |
| 500.48 | 4.60 | 4.60 |
| 472.43 | 3.82 | 3.82 |
| 502.45 | 3.44 | 3.44 |
| 529.52 | 3.75 | 3.75 |
| 515.50 | 3.36 | 3.36 |
| 500.44 | 3.73 | 3.73 |
| 502.45 | 3.44 | 3.44 |
| 528.49 | 3.98 | 3.98 |
| 543.51 | 3.28 | 3.28 |
| 526.52 | 4.99 | 4.99 |
| 504.44 | 4.50 | 4.50 |
| 504.44 | 4.50 | 4.50 |
| 500.48 | 4.60 | 4.60 |
| 526.52 | 4.99 | 4.99 |
| 446.35 | 2.47 | 2.47 |
| 470.64 | 2.78 | 2.78 |
| 533.62 | 3.41 | 3.41 |
| 533.62 | 3.41 | 3.41 |
| 515.63 | 3.27 | 3.27 |
| 533.62 | 3.41 | 3.41 |
| 502.06 | 3.78 | 3.78 |
| 485.60 | 3.26 | 3.26 |
| 551.61 | 4.02 | 4.02 |
| 525.69 | 3.91 | 3.91 |
| 507.50 | 3.34 | 3.34 |
| 454.57 | 2.31 | 2.31 |
| 486.45 | 3.50 | 3.50 |
| 479.44 | 3.27 | 3.27 |
| 495.49 | 3.89 | 3.89 |
| 441.35 | 1.89 | 1.89 |
| 439.34 | 1.66 | 1.66 |
| 446.35 | 1.89 | 1.89 |
| 433.31 | 1.60 | 1.60 |
| 454.57 | 2.31 | 2.31 |
| 385.46 | 2.09 | 2.09 |
| 438.39 | 3.12 | 3.12 |
| 431.37 | 3.67 | 3.67 |
| 503.63 | 3.42 | 3.42 |
| 526.46 | 4.30 | 4.30 |
| 533.47 | 4.52 | 4.52 |
| 475.03 | 2.85 | 2.85 |
| 524.89 | 3.00 | 3.00 |
| 512.02 | 4.46 | 4.46 |
| 459.03 | 3.15 | 3.15 |
| 485.03 | 3.59 | 3.59 |
| 463.02 | 2.42 | 2.42 |
| 465.06 | 3.21 | 3.21 |
| 520.02 | 3.32 | 3.32 |
| 414.30 | 2.76 | 2.76 |
| 480.39 | 1.81 | 1.81 |
| 416.50 | 0.78 | 0.78 |
| 472.66 | 3.03 | 3.03 |
| 461.40 | 3.44 | 3.44 |
| 456.61 | 2.39 | 2.39 |
| 508.49 | 2.43 | 2.43 |
| 416.55 | 1.47 | 1.47 |
| 430.57 | 1.86 | 1.86 |
| 485.65 | 1.54 | 1.54 |
| 457.56 | 0.93 | 0.93 |
| 495.49 | 3.91 | 3.91 |
| 421.31 | 2.98 | 2.98 |
| 502.50 | 4.13 | 4.13 |
| 515.50 | 2.65 | 2.65 |
| 446.39 | 2.57 | 2.57 |
| 487.40 | 2.04 | 2.04 |
| 426.34 | 2.44 | 2.44 |
| 453.41 | 2.74 | 2.74 |
| 449.35 | 1.50 | 1.50 |
| 503.49 | 3.50 | 3.50 |
| 447.33 | 1.28 | 1.28 |
| 402.88 | 1.17 | 1.17 |
| 464.34 | 2.02 | 2.02 |
| 453.36 | 1.34 | 1.34 |
| 384.43 | 2.05 | 2.05 |
| 504.44 | 4.35 | 4.35 |
| 383.45 | 1.45 | 1.45 |
| 448.36 | 2.11 | 2.11 |
| 466.35 | 2.25 | 2.25 |
| 385.46 | 1.68 | 1.68 |
| 504.44 | 4.35 | 4.35 |
| 500.48 | 4.52 | 4.52 |
| 520.90 | 4.86 | 4.86 |
| 390.87 | 1.72 | 1.72 |
| 402.52 | 1.26 | 1.26 |
| 442.59 | 1.91 | 1.91 |
| 425.35 | 2.01 | 2.01 |
| 453.41 | 2.92 | 2.92 |
| 487.42 | 3.45 | 3.45 |
| 453.41 | 2.77 | 2.77 |
| 432.36 | 2.23 | 2.23 |
| 458.40 | 2.76 | 2.76 |
| 432.36 | 2.36 | 2.36 |
| 494.43 | 3.67 | 3.67 |
| 494.43 | 3.67 | 3.67 |
| 460.42 | 2.99 | 2.99 |
| 472.43 | 3.01 | 3.01 |
| 507.50 | 3.34 | 3.34 |
| 368.44 | 1.15 | 1.15 |
| 522.43 | 4.49 | 4.49 |
| 522.43 | 4.49 | 4.49 |
| 522.43 | 4.49 | 4.49 |
| 536.46 | 4.16 | 4.16 |
| 520.49 | 4.25 | 4.25 |
| 478.41 | 3.28 | 3.28 |
| 464.38 | 2.89 | 2.89 |
| 518.47 | 4.03 | 4.03 |
| 451.39 | 2.54 | 2.54 |
| 465.42 | 2.79 | 2.79 |
| 465.42 | 2.87 | 2.87 |
| 480.42 | 3.50 | 3.50 |
| 536.46 | 4.16 | 4.16 |
| 536.46 | 4.16 | 4.16 |
| 536.46 | 4.16 | 4.16 |
| 453.41 | 2.76 | 2.76 |
| 426.38 | 3.67 | 3.67 |
| 541.51 | 4.32 | 4.32 |
| 555.54 | 4.71 | 4.71 |
| 455.42 | 3.14 | 3.14 |
| 441.40 | 2.75 | 2.75 |
| 467.43 | 3.09 | 3.09 |
| 467.43 | 3.01 | 3.01 |
| 505.43 | 3.74 | 3.74 |
| 432.36 | 3.07 | 3.07 |
| 446.39 | 3.46 | 3.46 |
| 439.64 | 3.81 | 3.81 |
| 469.71 | 4.53 | 4.53 |
| 436.60 | 2.56 | 2.56 |
| 456.61 | 3.10 | 3.10 |
| 482.57 | 3.92 | 3.92 |
| 475.56 | 3.54 | 3.54 |
| 449.64 | 3.74 | 3.74 |
| 470.64 | 2.78 | 2.78 |
| 474.02 | 3.92 | 3.92 |
| 412.53 | 2.74 | 2.74 |
| 470.64 | 2.78 | 2.78 |
| 449.60 | 3.65 | 3.65 |
| 518.47 | 4.03 | 4.03 |
| 518.47 | 4.03 | 4.03 |
| 475.56 | 3.54 | 3.54 |
| 427.55 | 1.81 | 1.81 |
| 507.57 | 4.28 | 4.28 |
| 449.64 | 3.74 | 3.74 |
| 463.62 | 3.33 | 3.33 |
| 487.59 | 3.72 | 3.72 |
| 452.60 | 2.53 | 2.53 |
| 507.57 | 4.28 | 4.28 |
| 463.62 | 3.33 | 3.33 |
| 524.03 | 4.80 | 4.80 |
| 507.57 | 4.28 | 4.28 |
| 507.57 | 4.28 | 4.28 |
| 491.46 | 3.83 | 3.83 |
| 449.64 | 3.74 | 3.74 |
| 442.63 | 3.52 | 3.52 |
| 465.64 | 3.44 | 3.44 |
| 492.01 | 4.06 | 4.06 |
| 479.67 | 3.91 | 3.91 |
| 488.05 | 4.22 | 4.22 |
| 532.08 | 3.79 | 3.79 |
| 527.66 | 3.14 | 3.14 |
| 527.66 | 3.14 | 3.14 |
| 495.66 | 3.18 | 3.18 |
| 511.66 | 3.17 | 3.17 |
| 560.53 | 3.93 | 3.93 |
| 509.69 | 3.78 | 3.78 |
| 495.66 | 3.47 | 3.47 |
| 499.63 | 3.31 | 3.31 |
| 525.65 | 2.89 | 2.89 |
| 590.56 | 3.94 | 3.94 |
| 509.69 | 3.78 | 3.78 |
| 511.66 | 3.52 | 3.52 |
| 470.06 | 3.82 | 3.82 |
| 415.97 | 2.50 | 2.50 |
| 449.98 | 3.58 | 3.58 |
| 528.07 | 2.83 | 2.83 |
| 504.50 | 4.47 | 4.47 |
| 498.11 | 4.45 | 4.45 |
| 550.49 | 4.21 | 4.21 |
| 493.47 | 3.66 | 3.66 |
| 554.45 | 5.23 | 5.23 |
| 402.52 | 1.13 | 1.13 |
| 514.51 | 4.99 | 4.99 |
| 546.51 | 4.60 | 4.60 |
| 550.47 | 4.16 | 4.16 |
| 576.53 | 4.22 | 4.22 |
| 568.46 | 4.45 | 4.45 |
| 553.47 | 3.97 | 3.97 |
| 414.32 | 2.00 | 2.00 |
| 428.35 | 2.40 | 2.40 |
| 442.38 | 2.79 | 2.79 |
| 442.38 | 2.78 | 2.78 |
| 458.38 | 2.02 | 2.02 |
| 468.42 | 3.32 | 3.32 |
| 482.44 | 3.71 | 3.71 |
| 482.44 | 3.56 | 3.56 |
| 482.44 | 3.56 | 3.56 |
| 439.38 | 2.37 | 2.37 |
| 427.37 | 2.23 | 2.23 |
| 441.40 | 2.62 | 2.62 |
| 453.41 | 2.76 | 2.76 |
| 453.41 | 2.76 | 2.76 |
| 467.43 | 3.15 | 3.15 |
| 467.43 | 3.01 | 3.01 |
| 425.35 | 1.98 | 1.98 |
| 472.43 | 3.85 | 3.85 |
| 472.43 | 3.85 | 3.85 |
| 513.00 | 3.86 | 3.86 |