Basic Information
ID: ALA3734552
Type: Functional
Description: Agonist activity at human recombinant ALX receptor expressed in HEK293 cells co-expressing G-protein Galpha16 assessed as effect on calcium response by Fluo-4-AM dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Lipoxin A4 receptor(ALA4227)
Document: ALA3727351
Agonist activity at human recombinant ALX receptor expressed in HEK293 cells co-expressing G-protein Galpha16 assessed as effect on calcium response by Fluo-4-AM dye based FLIPR assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3734552
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.47 | 3.66 | 3.66 |
| 470.68 | 4.20 | 4.20 |
| 491.66 | 3.96 | 3.96 |
| 499.08 | 4.71 | 4.71 |
| 502.70 | 4.28 | 4.28 |
| 489.66 | 3.05 | 3.05 |
| 474.65 | 3.58 | 3.58 |
| 465.64 | 3.17 | 3.17 |
| 497.44 | 4.24 | 4.24 |
| 518.41 | 5.30 | 5.30 |
| 500.44 | 3.73 | 3.73 |
| 499.84 | 5.23 | 5.23 |
| 433.35 | 3.37 | 3.37 |
| 474.40 | 3.20 | 3.20 |
| 498.25 | 4.92 | 4.92 |
| 475.38 | 3.68 | 3.68 |
| 431.37 | 4.52 | 4.52 |
| 500.46 | 4.65 | 4.65 |
| 517.43 | 4.83 | 4.83 |
| 446.35 | 2.60 | 2.60 |
| 466.38 | 4.35 | 4.35 |
| 417.35 | 3.99 | 3.99 |
| 486.45 | 4.06 | 4.06 |
| 480.41 | 4.36 | 4.36 |
| 447.37 | 3.71 | 3.71 |
| 503.80 | 5.44 | 5.44 |
| 486.45 | 4.21 | 4.21 |
| 469.38 | 3.69 | 3.69 |
| 443.39 | 4.52 | 4.52 |
| 486.44 | 4.34 | 4.34 |
| 432.36 | 2.89 | 2.89 |
| 513.86 | 5.57 | 5.57 |
| 483.41 | 4.03 | 4.03 |
| 429.36 | 4.13 | 4.13 |
| 533.47 | 4.85 | 4.85 |
| 518.46 | 5.45 | 5.45 |
| 417.35 | 4.13 | 4.13 |
| 497.41 | 5.10 | 5.10 |
| 477.40 | 5.05 | 5.05 |
| 503.83 | 4.34 | 4.34 |
| 470.64 | 2.78 | 2.78 |
| 449.60 | 3.65 | 3.65 |
| 428.60 | 3.21 | 3.21 |
| 469.65 | 3.39 | 3.39 |
| 453.58 | 2.92 | 2.92 |
| 455.60 | 3.14 | 3.14 |
| 477.57 | 4.69 | 4.69 |
| 454.57 | 2.31 | 2.31 |
| 483.41 | 3.91 | 3.91 |
| 547.48 | 3.73 | 3.73 |
| 468.64 | 3.31 | 3.31 |
| 506.51 | 3.95 | 3.95 |
| 518.47 | 4.03 | 4.03 |
| 460.37 | 2.81 | 2.81 |
| 492.37 | 2.60 | 2.60 |
| 486.41 | 3.34 | 3.34 |
| 418.29 | 1.82 | 1.82 |
| 529.52 | 3.75 | 3.75 |
| 500.48 | 4.60 | 4.60 |
| 472.43 | 3.82 | 3.82 |
| 502.45 | 3.44 | 3.44 |
| 529.52 | 3.75 | 3.75 |
| 515.50 | 3.36 | 3.36 |
| 500.44 | 3.73 | 3.73 |
| 502.45 | 3.44 | 3.44 |
| 528.49 | 3.98 | 3.98 |
| 543.51 | 3.28 | 3.28 |
| 526.52 | 4.99 | 4.99 |
| 504.44 | 4.50 | 4.50 |
| 504.44 | 4.50 | 4.50 |
| 500.48 | 4.60 | 4.60 |
| 526.52 | 4.99 | 4.99 |
| 446.35 | 2.47 | 2.47 |
| 470.64 | 2.78 | 2.78 |
| 533.62 | 3.41 | 3.41 |
| 533.62 | 3.41 | 3.41 |
| 515.63 | 3.27 | 3.27 |
| 533.62 | 3.41 | 3.41 |
| 502.06 | 3.78 | 3.78 |
| 485.60 | 3.26 | 3.26 |
| 551.61 | 4.02 | 4.02 |
| 525.69 | 3.91 | 3.91 |
| 507.50 | 3.34 | 3.34 |
| 454.57 | 2.31 | 2.31 |
| 486.45 | 3.50 | 3.50 |
| 479.44 | 3.27 | 3.27 |
| 495.49 | 3.89 | 3.89 |
| 441.35 | 1.89 | 1.89 |
| 439.34 | 1.66 | 1.66 |
| 446.35 | 1.89 | 1.89 |
| 433.31 | 1.60 | 1.60 |
| 454.57 | 2.31 | 2.31 |
| 385.46 | 2.09 | 2.09 |
| 438.39 | 3.12 | 3.12 |
| 431.37 | 3.67 | 3.67 |
| 503.63 | 3.42 | 3.42 |
| 526.46 | 4.30 | 4.30 |
| 533.47 | 4.52 | 4.52 |
| 475.03 | 2.85 | 2.85 |
| 524.89 | 3.00 | 3.00 |