Basic Information
ID: ALA3734567
Type: Binding
Description: Inhibition of Tet-induced Flag-tagged mouse TRPM7 expressed in HEK293 cells assessed as inhibition of channel-mediated cell death in presence of Mg2+ incubated for 24 to 48 hrs by propidium iodide uptake assay
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3734567
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.42 | 2.84 | 2.84 |
| 456.71 | 7.09 | 7.09 |
| 399.97 | 5.97 | 5.97 |
| 444.49 | -0.14 | -0.14 |
| 399.44 | 2.87 | 2.87 |
| 480.65 | 4.94 | 4.94 |
| 311.19 | 5.08 | 5.08 |
| 265.31 | 0.50 | 0.50 |
| 590.80 | 5.84 | 5.84 |
| 297.17 | 4.77 | 4.77 |
| 339.37 | 3.87 | 3.87 |
| 387.90 | 3.97 | 3.97 |
| 370.33 | 4.29 | 4.29 |
| 207.27 | 2.44 | 2.44 |
| 505.23 | 6.12 | 6.12 |
| 479.53 | 3.68 | 3.68 |
| 183.12 | -0.23 | -0.23 |
| 563.99 | 1.03 | 1.03 |
| 229.66 | 2.69 | 2.69 |
| 579.99 | 0.00 | 0.00 |
| 317.34 | 2.04 | 2.04 |
| 185.20 | 0.56 | 0.56 |
| 397.92 | 3.23 | 3.23 |
| 472.89 | 5.97 | 5.97 |
| 780.95 | 2.22 | 2.22 |
| 435.75 | 5.17 | 5.17 |
| 470.97 | 5.88 | 5.88 |
| 515.99 | 3.68 | 3.68 |
| 598.48 | 5.68 | 5.68 |
| 441.96 | 3.58 | 3.58 |
| 422.36 | 3.93 | 3.93 |
| 239.28 | 2.65 | 2.65 |
| 437.45 | 4.25 | 4.25 |
| 363.80 | 5.10 | 5.10 |
| 217.29 | 2.68 | 2.68 |
| 431.96 | 5.42 | 5.42 |
| 375.88 | 4.54 | 4.54 |
| 313.36 | 3.30 | 3.30 |
| 276.34 | 4.49 | 4.49 |
| 263.38 | 2.45 | 2.45 |
| 381.84 | 3.59 | 3.59 |
| 282.73 | 4.14 | 4.14 |
| 366.44 | 3.55 | 3.55 |
| 339.40 | 3.29 | 3.29 |
| 384.84 | 4.80 | 4.80 |
| 283.33 | 4.00 | 4.00 |
| 314.34 | 4.29 | 4.29 |
| 252.34 | 4.06 | 4.06 |
| 320.39 | 4.64 | 4.64 |
| 364.52 | 4.60 | 4.60 |
| 294.24 | 2.82 | 2.82 |
| 397.91 | 4.22 | 4.22 |
| 234.26 | 3.43 | 3.43 |
| 372.51 | 4.13 | 4.13 |
| 412.43 | 3.19 | 3.19 |
| 411.91 | 3.03 | 3.03 |
| 416.45 | 3.15 | 3.15 |
| 236.30 | 2.54 | 2.54 |
| 404.43 | 2.14 | 2.14 |
| 321.42 | 3.50 | 3.50 |
| 465.42 | 3.41 | 3.41 |
| 290.39 | 4.33 | 4.33 |
| 348.45 | 3.41 | 3.41 |
| 266.30 | 2.08 | 2.08 |
| 415.54 | 2.63 | 2.63 |
| 294.70 | 2.10 | 2.10 |
| 248.35 | 3.00 | 3.00 |
| 238.70 | 1.92 | 1.92 |
| 282.13 | 3.26 | 3.26 |
| 544.44 | -0.79 | -0.79 |
| 264.32 | 4.58 | 4.58 |
| 384.39 | 4.31 | 4.31 |
| 401.37 | 4.40 | 4.40 |
| 370.39 | 3.45 | 3.45 |
| 287.43 | 4.84 | 4.84 |
| 326.79 | 2.98 | 2.98 |
| 330.78 | 3.80 | 3.80 |
| 341.86 | 5.46 | 5.46 |
| 357.86 | 5.16 | 5.16 |
| 357.86 | 4.97 | 4.97 |
| 335.19 | 4.70 | 4.70 |
| 364.52 | 4.60 | 4.60 |
| 350.49 | 4.25 | 4.25 |
| 401.91 | 3.61 | 3.61 |
| 318.48 | 5.80 | 5.80 |
| 327.84 | 4.75 | 4.75 |
| 316.86 | 4.80 | 4.80 |
| 374.68 | 4.28 | 4.28 |
| 570.26 | 7.41 | 7.41 |
| 367.92 | 6.63 | 6.63 |
| 386.95 | 5.67 | 5.67 |
| 365.48 | 3.18 | 3.18 |
| 450.97 | 4.56 | 4.56 |
| 364.81 | 3.19 | 3.19 |
| 361.32 | 3.14 | 3.14 |
| 385.87 | 4.80 | 4.80 |
| 306.29 | 3.65 | 3.65 |
| 368.36 | 4.61 | 4.61 |
| 283.37 | 3.25 | 3.25 |
| 478.01 | 6.67 | 6.67 |
| 264.30 | 3.81 | 3.81 |
| 416.52 | 6.21 | 6.21 |
| 312.35 | 0.99 | 0.99 |
| 478.37 | 2.52 | 2.52 |
| 396.24 | 4.57 | 4.57 |
| 446.36 | 4.25 | 4.25 |
| 306.41 | 3.18 | 3.18 |
| 183.24 | 1.44 | 1.44 |
| 365.33 | 5.26 | 5.26 |
| 501.74 | 5.05 | 5.05 |
| 400.67 | 5.22 | 5.22 |
| 508.46 | 4.53 | 4.53 |
| 410.01 | 6.59 | 6.59 |
| 290.20 | 3.48 | 3.48 |
| 310.35 | 3.03 | 3.03 |
| 287.40 | 4.53 | 4.53 |
| 331.23 | 4.61 | 4.61 |
| 299.37 | 4.82 | 4.82 |
| 337.51 | 5.19 | 5.19 |
| 273.38 | 3.47 | 3.47 |
| 222.22 | 2.27 | 2.27 |
| 265.67 | 3.44 | 3.44 |
| 318.11 | 4.23 | 4.23 |
| 312.11 | 4.12 | 4.12 |
| 371.22 | 5.19 | 5.19 |
| 348.19 | 5.18 | 5.18 |
| 260.29 | 3.15 | 3.15 |
| 290.78 | 3.97 | 3.97 |
| 466.15 | 4.38 | 4.38 |
| 312.42 | 3.14 | 3.14 |
| 331.85 | 3.40 | 3.40 |
| 338.79 | 5.78 | 5.78 |
| 324.62 | 4.39 | 4.39 |
| 258.12 | 3.42 | 3.42 |
| 227.25 | 0.68 | 0.68 |
| 344.77 | 5.00 | 5.00 |
| 604.51 | 7.31 | 7.31 |
| 369.90 | 4.62 | 4.62 |
| 252.22 | 1.66 | 1.66 |
| 427.33 | 4.62 | 4.62 |
| 400.93 | 6.92 | 6.92 |
| 341.39 | 2.27 | 2.27 |
| 408.94 | 3.16 | 3.16 |
| 303.43 | 4.21 | 4.21 |
| 286.28 | 3.49 | 3.49 |
| 485.38 | 2.04 | 2.04 |
| 386.30 | 3.67 | 3.67 |
| 431.34 | 6.14 | 6.14 |
| 247.29 | 2.56 | 2.56 |
| 396.87 | 3.18 | 3.18 |
| 405.37 | 3.60 | 3.60 |
| 484.27 | 5.14 | 5.14 |
| 473.37 | 5.39 | 5.39 |
| 456.95 | 4.94 | 4.94 |
| 409.68 | 3.31 | 3.31 |
| 323.83 | 3.64 | 3.64 |
| 343.39 | 4.78 | 4.78 |
| 400.54 | 4.36 | 4.36 |
| 308.36 | 3.51 | 3.51 |
| 347.46 | 4.46 | 4.46 |
| 348.45 | 3.41 | 3.41 |
| 378.48 | 3.42 | 3.42 |
| 405.33 | 4.89 | 4.89 |
| 336.41 | 3.54 | 3.54 |
| 363.44 | 4.31 | 4.31 |
| 323.42 | 3.62 | 3.62 |
| 349.43 | 3.21 | 3.21 |
| 323.42 | 3.94 | 3.94 |
| 339.42 | 4.59 | 4.59 |
| 357.87 | 5.72 | 5.72 |
| 358.40 | 4.07 | 4.07 |
| 452.96 | 3.59 | 3.59 |
| 389.82 | 3.08 | 3.08 |
| 315.35 | 2.32 | 2.32 |
| 290.35 | 3.07 | 3.07 |
| 328.32 | 4.08 | 4.08 |
| 360.46 | 5.73 | 5.73 |
| 310.38 | 5.18 | 5.18 |
| 360.46 | 6.30 | 6.30 |
| 256.30 | 4.16 | 4.16 |
| 331.26 | 4.56 | 4.56 |
| 309.37 | 3.89 | 3.89 |
| 353.42 | 4.21 | 4.21 |
| 430.37 | -0.84 | -0.84 |
| 201.65 | 1.09 | 1.09 |
| 333.86 | 5.28 | 5.28 |
| 593.77 | 1.00 | 1.00 |
| 402.76 | 3.91 | 3.91 |
| 385.31 | 1.38 | 1.38 |
| 363.15 | 3.09 | 3.09 |
| 333.48 | 2.73 | 2.73 |
| 224.29 | 3.77 | 3.77 |
| 213.66 | 0.79 | 0.79 |
| 199.32 | 2.87 | 2.87 |
| 292.38 | 2.26 | 2.26 |
| 270.40 | 4.77 | 4.77 |
| 312.38 | 2.94 | 2.94 |
| 243.31 | 1.58 | 1.58 |
| 177.21 | 1.29 | 1.29 |
| 283.81 | 3.98 | 3.98 |
| 346.84 | 4.21 | 4.21 |
| 349.80 | 2.95 | 2.95 |
| 325.82 | 2.84 | 2.84 |
| 419.48 | 2.89 | 2.89 |
| 222.34 | 2.96 | 2.96 |
| 277.21 | 3.75 | 3.75 |
| 382.71 | 5.09 | 5.09 |
| 320.40 | 3.88 | 3.88 |
| 445.39 | 3.74 | 3.74 |
| 370.84 | 3.05 | 3.05 |
| 375.88 | 4.39 | 4.39 |
| 398.72 | 4.49 | 4.49 |
| 319.84 | 4.63 | 4.63 |
| 434.97 | 5.77 | 5.77 |
| 470.97 | 5.51 | 5.51 |
| 258.32 | 0.77 | 0.77 |
| 320.42 | 4.37 | 4.37 |
| 163.18 | 1.43 | 1.43 |
| 405.27 | 5.21 | 5.21 |
| 374.37 | 2.57 | 2.57 |
| 274.21 | 3.01 | 3.01 |
| 312.16 | 1.86 | 1.86 |
| 301.37 | 2.68 | 2.68 |
| 295.37 | 3.02 | 3.02 |
| 296.39 | 0.66 | 0.66 |
| 287.26 | 3.43 | 3.43 |
| 182.15 | 1.22 | 1.22 |
| 405.74 | 6.55 | 6.55 |
| 383.51 | 1.83 | 1.83 |
| 374.41 | 3.19 | 3.19 |
| 478.52 | 4.45 | 4.45 |
| 362.31 | 4.62 | 4.62 |
| 406.43 | 5.74 | 5.74 |
| 336.43 | 2.74 | 2.74 |
| 305.36 | 3.41 | 3.41 |
| 367.45 | 5.67 | 5.67 |
| 467.52 | 3.56 | 3.56 |
| 404.97 | 4.95 | 4.95 |
| 237.20 | 2.12 | 2.12 |
| 231.15 | 3.10 | 3.10 |
| 416.55 | 3.74 | 3.74 |
| 246.34 | 3.38 | 3.38 |
| 170.62 | 2.34 | 2.34 |
| 278.76 | 4.19 | 4.19 |
| 322.84 | 3.93 | 3.93 |
| 372.30 | 5.32 | 5.32 |
| 282.39 | 2.14 | 2.14 |
| 391.85 | 5.57 | 5.57 |
| 354.82 | 2.67 | 2.67 |
| 266.37 | 1.30 | 1.30 |
| 323.62 | 3.96 | 3.96 |
| 258.23 | 2.55 | 2.55 |
| 397.84 | 3.24 | 3.24 |
| 340.27 | 5.26 | 5.26 |
| 371.86 | 5.95 | 5.95 |
| 314.37 | 3.09 | 3.09 |
| 332.81 | 4.04 | 4.04 |
| 335.77 | 4.20 | 4.20 |
| 475.68 | 7.13 | 7.13 |
| 450.24 | 8.13 | 8.13 |
| 429.14 | 3.74 | 3.74 |
| 246.74 | 3.88 | 3.88 |
| 562.53 | ||
| 456.61 | 7.39 | 7.39 |
| 311.34 | 4.42 | 4.42 |
| 387.42 | 4.26 | 4.26 |
| 389.86 | 5.52 | 5.52 |
| 447.27 | 6.18 | 6.18 |
| 481.59 | 7.00 | 7.00 |
| 328.39 | 3.18 | 3.18 |
| 360.52 | 4.63 | 4.63 |
| 405.56 | 5.49 | 5.49 |
| 373.52 | 4.39 | 4.39 |
| 365.48 | 5.28 | 5.28 |
| 337.30 | 5.20 | 5.20 |
| 374.48 | 6.04 | 6.04 |
| 356.38 | 4.82 | 4.82 |
| 318.40 | 5.15 | 5.15 |
| 240.37 | 3.50 | 3.50 |
| 327.25 | 2.07 | 2.07 |
| 161.16 | 1.78 | 1.78 |
| 248.28 | 0.99 | 0.99 |
| 404.41 | 0.88 | 0.88 |
| 620.56 | -0.91 | -0.91 |
| 327.43 | 5.37 | 5.37 |
| 163.22 | 2.26 | 2.26 |
| 247.34 | 2.64 | 2.64 |
| 407.43 | 4.32 | 4.32 |
| 311.33 | 2.14 | 2.14 |
| 373.91 | 4.91 | 4.91 |
| 306.15 | 4.21 | 4.21 |
| 203.24 | 1.81 | 1.81 |
| 271.11 | 2.21 | 2.21 |
| 382.87 | 5.95 | 5.95 |
| 349.22 | 4.40 | 4.40 |
| 484.21 | 6.30 | 6.30 |
| 459.34 | 4.23 | 4.23 |
| 412.56 | 4.81 | 4.81 |
| 384.71 | 4.27 | 4.27 |
| 337.16 | 4.10 | 4.10 |
| 451.33 | 5.54 | 5.54 |
| 276.33 | 3.38 | 3.38 |
| 301.56 | 4.50 | 4.50 |
| 323.81 | 2.44 | 2.44 |
| 318.39 | 3.42 | 3.42 |
| 372.21 | 5.90 | 5.90 |
| 333.21 | 5.21 | 5.21 |
| 475.98 | 5.92 | 5.92 |
| 306.46 | 4.01 | 4.01 |
| 364.92 | 6.04 | 6.04 |
| 385.39 | 6.15 | 6.15 |
| 487.40 | 7.42 | 7.42 |
| 336.34 | 4.80 | 4.80 |
| 302.79 | 4.50 | 4.50 |
| 374.36 | 5.09 | 5.09 |
| 333.29 | 4.19 | 4.19 |
| 371.22 | 5.45 | 5.45 |
| 283.39 | 1.68 | 1.68 |
| 311.26 | 3.51 | 3.51 |
| 351.41 | 5.00 | 5.00 |
| 528.31 | 7.01 | 7.01 |
| 292.72 | 2.71 | 2.71 |
| 288.66 | 3.83 | 3.83 |
| 233.34 | 1.30 | 1.30 |
| 341.35 | 2.20 | 2.20 |
| 458.44 | 5.14 | 5.14 |
| 317.72 | 4.69 | 4.69 |
| 292.21 | 1.50 | 1.50 |
| 421.31 | 4.87 | 4.87 |
| 335.35 | 4.95 | 4.95 |
| 371.30 | 3.44 | 3.44 |
| 399.86 | 4.40 | 4.40 |
| 296.33 | 3.17 | 3.17 |
| 491.79 | 6.49 | 6.49 |
| 350.37 | 4.40 | 4.40 |
| 397.50 | 3.77 | 3.77 |
| 370.78 | 5.47 | 5.47 |
| 423.27 | 3.40 | 3.40 |
| 289.29 | 1.80 | 1.80 |
| 251.28 | 1.59 | 1.59 |
| 433.35 | 5.01 | 5.01 |
| 379.44 | 3.98 | 3.98 |
| 396.76 | 4.47 | 4.47 |
| 433.82 | 4.32 | 4.32 |
| 354.44 | 5.09 | 5.09 |
| 322.75 | 2.49 | 2.49 |
| 402.86 | 5.64 | 5.64 |
| 500.88 | 5.57 | 5.57 |
| 376.44 | 4.29 | 4.29 |
| 292.41 | 4.33 | 4.33 |
| 230.27 | 2.25 | 2.25 |
| 416.40 | 4.04 | 4.04 |
| 416.35 | 6.10 | 6.10 |
| 317.37 | 2.24 | 2.24 |
| 460.56 | 4.89 | 4.89 |
| 434.56 | 3.88 | 3.88 |
| 308.96 | 2.74 | 2.74 |
| 252.36 | 2.73 | 2.73 |
| 313.36 | 3.95 | 3.95 |