Basic Information
ID: ALA3736700
Type: Functional
Description: Antagonist activity at human recombinant 5-HT2B receptor expressed in Flp-In HEK cells in the presence of agonist preincubated for 10 mins by FLIPR based calcium mobilization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Serotonin 2b (5-HT2b) receptor(ALA1833)
Document: ALA3734659
Antagonist activity at human recombinant 5-HT2B receptor expressed in Flp-In HEK cells in the presence of agonist preincubated for 10 mins by FLIPR based calcium mobilization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3736700
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.55 | 4.76 | 4.76 |
| 447.58 | 5.15 | 5.15 |
| 477.60 | 5.16 | 5.16 |
| 477.60 | 5.16 | 5.16 |
| 477.60 | 5.16 | 5.16 |
| 507.63 | 5.17 | 5.17 |
| 537.65 | 5.18 | 5.18 |
| 523.63 | 5.14 | 5.14 |
| 445.56 | 5.58 | 5.58 |