Assay Report Card

Basic Information

ID: ALA3736923

Type: Functional

Description: Neuroprotective activity in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as reduction of dead neurons in dentate gyrus region of hippocampus at 30 mg/kg/day administered as intragastric infusion for 32 days measured 24 hrs post last dose by hematoxylin and eosin staining based microscopic analysis (Rvb = 80.1 +/- 10.8 % )

Organism: Rattus norvegicus

Strain: Wistar

Tissue: Gyrus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
305.503.203.20
439.644.664.66