Basic Information
ID: ALA3737385
Type: Functional
Description: Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux in presence of EC20 glutamate
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U2OS
Target: Metabotropic glutamate receptor 5(ALA3227)
Document: ALA3734684
Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux in presence of EC20 glutamate: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3737385
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.40 | 3.85 | 3.85 |
| 379.37 | 3.87 | 3.87 |
| 380.36 | 3.26 | 3.26 |
| 382.44 | 3.01 | 3.01 |
| 355.37 | 2.70 | 2.70 |
| 327.36 | 3.32 | 3.32 |
| 341.39 | 3.49 | 3.49 |
| 383.43 | 3.27 | 3.27 |
| 355.42 | 3.79 | 3.79 |
| 352.37 | 3.00 | 3.00 |
| 338.42 | 3.06 | 3.06 |
| 332.41 | 1.53 | 1.53 |
| 303.41 | 2.89 | 2.89 |
| 329.45 | 3.74 | 3.74 |
| 355.42 | 3.42 | 3.42 |
| 366.47 | 3.42 | 3.42 |
| 348.41 | 3.23 | 3.23 |
| 341.39 | 3.49 | 3.49 |
| 341.39 | 3.49 | 3.49 |
| 340.41 | 3.16 | 3.16 |
| 349.37 | 4.40 | 4.40 |