Basic Information
ID: ALA3742598
Type: Binding
Description: Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residual activity measured every 30 to 60 seconds for 60 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3742598
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 5.45 | 5.45 |
| 354.41 | 4.46 | 4.46 |
| 383.48 | 5.75 | 5.75 |
| 370.41 | 4.84 | 4.84 |
| 340.43 | 5.45 | 5.45 |
| 371.40 | 5.05 | 5.05 |
| 326.40 | 5.14 | 5.14 |
| 395.42 | 4.71 | 4.71 |
| 384.44 | 5.15 | 5.15 |
| 449.30 | 5.60 | 5.60 |
| 388.40 | 4.98 | 4.98 |
| 351.41 | 5.01 | 5.01 |
| 450.29 | 5.81 | 5.81 |
| 398.46 | 5.32 | 5.32 |
| 466.46 | 6.34 | 6.34 |
| 416.45 | 5.46 | 5.46 |
| 432.91 | 5.97 | 5.97 |
| 371.40 | 4.24 | 4.24 |
| 371.40 | 4.24 | 4.24 |
| 376.46 | 5.37 | 5.37 |
| 332.45 | 5.67 | 5.67 |
| 390.48 | 5.46 | 5.46 |
| 250.30 | 3.55 | 3.55 |
| 338.41 | 5.15 | 5.15 |
| 441.27 | 6.18 | 6.18 |
| 485.28 | 5.88 | 5.88 |
| 454.61 | 7.88 | 7.88 |
| 325.41 | 5.75 | 5.75 |
| 381.52 | 7.04 | 7.04 |
| 369.42 | 5.45 | 5.45 |
| 369.42 | 5.45 | 5.45 |
| 448.32 | 6.21 | 6.21 |
| 397.47 | 5.84 | 5.84 |
| 404.31 | 6.51 | 6.51 |
| 325.41 | 5.75 | 5.75 |
| 341.41 | 5.45 | 5.45 |
| 351.41 | 5.01 | 5.01 |
| 370.41 | 4.84 | 4.84 |
| 460.53 | 6.50 | 6.50 |
| 360.84 | 5.80 | 5.80 |
| 405.30 | 5.90 | 5.90 |
| 376.46 | 6.30 | 6.30 |
| 310.40 | 5.44 | 5.44 |
| 309.41 | 6.04 | 6.04 |
| 440.29 | 6.79 | 6.79 |
| 484.30 | 6.49 | 6.49 |
| 353.47 | 5.99 | 5.99 |
| 331.42 | 5.06 | 5.06 |
| 410.31 | 5.83 | 5.83 |
| 489.21 | 6.59 | 6.59 |
| 303.36 | 4.59 | 4.59 |
| 382.26 | 5.35 | 5.35 |
| 461.15 | 6.11 | 6.11 |
| 378.48 | 6.14 | 6.14 |
| 457.37 | 6.90 | 6.90 |
| 536.27 | 7.67 | 7.67 |
| 428.54 | 7.29 | 7.29 |
| 422.48 | 5.84 | 5.84 |