Basic Information
ID: ALA3742871
Type: Binding
Description: Inhibition of human TNF assessed as reduction in TNF-induced cell death of actinomycin D activated mouse L929 cells at 20 uM preincubated for 30 mins followed by cell addition measured after 18 to 24 hrs by crystal violet staining based spectrophotometric analysis
Organism: Homo sapiens
Cell type: L929
Activity Charts
Bioactivity
Activity Types for Assay ALA3742871
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.62 | 6.94 | 6.94 |
| 545.61 | 6.69 | 6.69 |
| 533.59 | 6.63 | 6.63 |
| 531.58 | 6.38 | 6.38 |
| 575.59 | 6.22 | 6.22 |
| 492.54 | 3.92 | 3.92 |
| 543.60 | 3.83 | 3.83 |
| 541.59 | 3.58 | 3.58 |
| 588.60 | 3.74 | 3.74 |
| 586.58 | 3.49 | 3.49 |
| 558.62 | 3.41 | 3.41 |
| 556.60 | 3.17 | 3.17 |
| 507.55 | 3.50 | 3.50 |
| 567.51 | 4.15 | 4.15 |
| 531.53 | 5.71 | 5.71 |
| 513.56 | 6.76 | 6.76 |
| 463.50 | 5.61 | 5.61 |
| 529.57 | 3.53 | 3.53 |