Basic Information
ID: ALA3743579
Type: Binding
Description: Antagonist activity at P2X7R in human whole blood assessed as inhibition of LPS-induced IL-1beta production incubated for 30 mins followed by ATP addition for 30 mins by ELISA assay
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3743579
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.85 | 3.28 | 3.28 |
| 449.28 | 3.73 | 3.73 |
| 464.47 | 3.50 | 3.50 |
| 436.42 | 3.18 | 3.18 |
| 537.55 | 1.32 | 1.32 |
| 432.46 | 3.50 | 3.50 |
| 408.43 | 2.60 | 2.60 |
| 446.48 | 3.36 | 3.36 |
| 432.45 | 3.35 | 3.35 |
| 476.51 | 2.82 | 2.82 |
| 432.46 | 3.15 | 3.15 |