Basic Information
ID: ALA3743582
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as GSH adduct UV peak area at 20 uM preincubated for 5 mins followed by NADPH addition measured after 60 mins by LC/MS/MS analysis relative to total area of GSH adduct, other metabolites, parent compound
Organism: Homo sapiens
Tissue: Liver
Activity Charts
Bioactivity
Activity Types for Assay ALA3743582
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.28 | 4.67 | 4.67 |
| 437.24 | 4.80 | 4.80 |
| 453.70 | 5.31 | 5.31 |
| 418.85 | 4.22 | 4.22 |
| 418.85 | 3.28 | 3.28 |
| 464.47 | 3.50 | 3.50 |
| 537.55 | 1.32 | 1.32 |