Basic Information
ID: ALA3744105
Type: Functional
Description: Antagonist activity against human GPR40 expressed in HEK293s FLPIN cells assessed as elaidic acid stimulated IP1 release after 2 hrs by TR-FRET analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3744105
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 277.33 | 3.43 | 3.43 |
| 311.77 | 4.08 | 4.08 |
| 311.77 | 4.08 | 4.08 |
| 311.77 | 4.08 | 4.08 |
| 307.35 | 3.43 | 3.43 |
| 307.35 | 3.43 | 3.43 |
| 307.35 | 3.43 | 3.43 |
| 302.34 | 3.30 | 3.30 |
| 302.34 | 3.30 | 3.30 |
| 302.34 | 3.30 | 3.30 |
| 334.38 | 3.38 | 3.38 |
| 334.38 | 3.38 | 3.38 |
| 334.38 | 3.38 | 3.38 |
| 355.42 | 2.83 | 2.83 |
| 355.42 | 2.83 | 2.83 |
| 355.42 | 2.83 | 2.83 |
| 295.32 | 3.57 | 3.57 |
| 295.32 | 3.57 | 3.57 |
| 295.32 | 3.57 | 3.57 |
| 313.31 | 3.70 | 3.70 |
| 313.31 | 3.70 | 3.70 |
| 313.31 | 3.70 | 3.70 |
| 331.30 | 3.84 | 3.84 |
| 331.30 | 3.84 | 3.84 |
| 331.30 | 3.84 | 3.84 |
| 331.30 | 3.84 | 3.84 |
| 331.30 | 3.84 | 3.84 |
| 331.30 | 3.84 | 3.84 |
| 311.32 | 3.27 | 3.27 |
| 325.34 | 3.66 | 3.66 |
| 324.36 | 3.32 | 3.32 |
| 324.36 | 3.69 | 3.69 |
| 338.39 | 4.08 | 4.08 |
| 400.40 | 4.38 | 4.38 |
| 388.35 | 2.72 | 2.72 |
| 414.39 | 3.51 | 3.51 |
| 478.50 | 3.41 | 3.41 |
| 411.39 | 3.88 | 3.88 |
| 415.29 | 4.48 | 4.48 |
| 401.39 | 4.71 | 4.71 |
| 403.36 | 3.56 | 3.56 |
| 417.39 | 3.95 | 3.95 |
| 433.39 | 3.33 | 3.33 |
| 442.40 | 3.84 | 3.84 |
| 421.35 | 3.65 | 3.65 |
| 348.41 | 2.95 | 2.95 |
| 288.35 | 3.90 | 3.90 |