Basic Information
ID: ALA3744247
Type: Binding
Description: Negative allosteric modulation of rat GluN1a/GluN2B receptor expressed in Xenopus laevis oocytes assessed as suppression of 100 uM glutamate and 30 uM glycine induced-current at 30 uM by voltage clamp recording method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3744247
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 313.36 | 1.03 | 1.03 |
| 355.44 | 2.04 | 2.04 |
| 423.56 | 2.97 | 2.97 |
| 353.43 | 1.82 | 1.82 |
| 368.44 | 2.09 | 2.09 |
| 382.46 | 2.48 | 2.48 |
| 409.53 | 2.69 | 2.69 |
| 365.41 | 1.34 | 1.34 |