Basic Information
ID: ALA3744462
Type: Binding
Description: Negative allosteric modulation of rat GluN1a/GluN2B receptor expressed in Xenopus laevis oocytes assessed as suppression of 100 uM glutamate and 30 uM glycine induced-current at saturating compound level by voltage clamp recording method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3744462
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.41 | 1.65 | 1.65 |
| 355.44 | 1.98 | 1.98 |
| 381.48 | 2.30 | 2.30 |
| 367.45 | 1.70 | 1.70 |
| 381.48 | 1.94 | 1.94 |
| 395.51 | 2.33 | 2.33 |
| 341.41 | 1.38 | 1.38 |
| 341.41 | 1.73 | 1.73 |
| 355.44 | 1.90 | 1.90 |
| 409.53 | 2.93 | 2.93 |
| 409.53 | 2.93 | 2.93 |
| 417.46 | 2.54 | 2.54 |
| 399.52 | 2.21 | 2.21 |
| 383.45 | 1.49 | 1.49 |