Assay Report Card

Basic Information

ID: ALA3744696

Type: Binding

Description: Inhibition of IKK in human MDA-MB-231 cells assessed as inhibition of TNF-alpha-induced p65/RelA phosphorylation at Ser-536 residue in nucleus at 10 uM pretreated for 30 mins followed by addition of TNF-alpha for 1 hr by immunofluorescence analysis

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
314.343.313.31