Basic Information
ID: ALA3744696
Type: Binding
Description: Inhibition of IKK in human MDA-MB-231 cells assessed as inhibition of TNF-alpha-induced p65/RelA phosphorylation at Ser-536 residue in nucleus at 10 uM pretreated for 30 mins followed by addition of TNF-alpha for 1 hr by immunofluorescence analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: Inhibitor of NF-kappa-B kinase (IKK)(ALA2111328)
Document: ALA3739305
Inhibition of IKK in human MDA-MB-231 cells assessed as inhibition of TNF-alpha-induced p65/RelA phosphorylation at Ser-536 residue in nucleus at 10 uM pretreated for 30 mins followed by addition of TNF-alpha for 1 hr by immunofluorescence analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3744696
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.34 | 3.31 | 3.31 |