Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced ethidium ion uptake at 1 uM after 2 hrs

Basic Information

ID: ALA3745025

Type: Binding

Description: Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced ethidium ion uptake at 1 uM after 2 hrs

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  P2X purinoceptor 7(ALA4805)

Document:  ALA3739377

Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced ethidium ion uptake at 1 uM after 2 hrs: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
569.643.233.23
587.633.373.37
587.633.373.37
583.673.543.54
614.643.143.14
637.644.254.25
597.652.752.75
715.794.974.97
493.551.311.31
577.662.602.60
563.642.212.21
577.662.602.60
563.642.352.35