ID: ALA3745170
Type: Binding
Description: Noncompetitive negative allosteric modulation of rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as suppression of 1000 uM glutamate and 30 uM glycine induced-current at 5 uM by voltage clamp recording method relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Glutamate NMDA receptor; Grin1/Grin2c(ALA2096911)
Document: ALA3739344
Noncompetitive negative allosteric modulation of rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as suppression of 1000 uM glutamate and 30 uM glycine induced-current at 5 uM by voltage clamp recording method relative to control: 1
Bioactivity
Activity Types for Assay ALA3745170
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
395.51 | 2.33 | 2.33 |