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Noncompetitive negative allosteric modulation of rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as suppression of 1000 uM glu...

Basic Information

ID: ALA3745170

Type: Binding

Description: Noncompetitive negative allosteric modulation of rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as suppression of 1000 uM glutamate and 30 uM glycine induced-current at 5 uM by voltage clamp recording method relative to control

Format: BAO_0000219

Organism: Rattus norvegicus

Target:  Glutamate NMDA receptor; Grin1/Grin2c(ALA2096911)

Document:  ALA3739344

Noncompetitive negative allosteric modulation of rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as suppression of 1000 uM glutamate and 30 uM glycine induced-current at 5 uM by voltage clamp recording method relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
395.512.332.33