Basic Information
ID: ALA3745177
Type: Binding
Description: Voltage-independent negative allosteric modulation of rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as mean reverse potential of 100 uM glutamate and 30 uM glycine induced-current at -60 to +60 mV at 3 uM by voltage clamp recording method in absence of Mg2+ (Rvb=-13+/-0.6 mV)
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3745177
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.51 | 2.33 | 2.33 |