Basic Information
ID: ALA3745355
Type: Binding
Description: Inhibition of recombinant human AKR1B10 expressed in human HCT116 cells assessed as reduction in daunorubicinol production using daunorubicin as substrate at 20 uM incubated for 4 to 8 hrs by UHPLC based transient transfection assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: Aldo-keto reductase family 1 member B10(ALA5983)
Document: ALA3739262
Inhibition of recombinant human AKR1B10 expressed in human HCT116 cells assessed as reduction in daunorubicinol production using daunorubicin as substrate at 20 uM incubated for 4 to 8 hrs by UHPLC based transient transfection assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3745355
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 302.24 | 1.99 | 1.99 |
| 238.24 | 3.17 | 3.17 |
| 286.24 | 2.28 | 2.28 |