Basic Information
ID: ALA3745429
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 30 mins
Format: BAO_0000019
Organism: Mycobacterium tuberculosis
Target: DNA gyrase subunit A/DNA gyrase subunit B(ALA3430898)
Document: ALA3739357
Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 30 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3745429
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.44 | 2.37 | 2.37 |
| 612.63 | 3.63 | 3.63 |
| 204.31 | -0.29 | -0.29 |
| 407.47 | 2.25 | 2.25 |
| 425.46 | 2.39 | 2.39 |
| 441.92 | 2.91 | 2.91 |
| 449.51 | 2.46 | 2.46 |
| 452.47 | 2.16 | 2.16 |
| 486.37 | 3.02 | 3.02 |
| 421.50 | 2.56 | 2.56 |
| 423.54 | 2.42 | 2.42 |
| 441.53 | 2.56 | 2.56 |
| 457.99 | 3.07 | 3.07 |
| 465.58 | 2.62 | 2.62 |
| 468.54 | 2.33 | 2.33 |
| 502.44 | 3.18 | 3.18 |
| 437.57 | 2.73 | 2.73 |
| 451.53 | 1.94 | 1.94 |
| 455.95 | 2.59 | 2.59 |
| 467.60 | 2.11 | 2.11 |
| 472.01 | 2.75 | 2.75 |
| 378.48 | 2.22 | 2.22 |
| 412.92 | 2.88 | 2.88 |
| 396.47 | 2.36 | 2.36 |
| 408.50 | 2.23 | 2.23 |
| 423.47 | 2.13 | 2.13 |
| 457.37 | 2.99 | 2.99 |