Basic Information
ID: ALA3749686
Type: Binding
Description: Inhibition of COX2 in rat abdominal macrophages assessed as PGE2 production pretreated for 30 mins followed by addition of 10 uM arachidonic acid as substrate for 20 mins by EIA
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3749686
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 635.72 | 3.74 | 3.74 |
| 568.65 | 4.20 | 4.20 |
| 672.58 | 5.38 | 5.38 |
| 611.67 | 4.76 | 4.76 |
| 607.71 | 4.93 | 4.93 |
| 593.68 | 4.62 | 4.62 |
| 661.68 | 5.64 | 5.64 |
| 551.65 | 4.40 | 4.40 |
| 619.64 | 5.42 | 5.42 |
| 598.54 | 5.84 | 5.84 |
| 585.51 | 4.69 | 4.69 |
| 639.68 | 4.68 | 4.68 |
| 621.69 | 4.54 | 4.54 |
| 689.69 | 5.56 | 5.56 |
| 714.62 | 5.69 | 5.69 |
| 701.58 | 4.54 | 4.54 |
| 640.67 | 3.92 | 3.92 |
| 622.68 | 3.78 | 3.78 |
| 654.70 | 4.31 | 4.31 |
| 636.71 | 4.17 | 4.17 |
| 537.62 | 4.10 | 4.10 |
| 630.54 | 5.25 | 5.25 |
| 569.64 | 4.63 | 4.63 |
| 538.61 | 3.34 | 3.34 |
| 552.63 | 3.73 | 3.73 |
| 638.70 | 4.25 | 4.25 |
| 713.63 | 5.26 | 5.26 |
| 652.73 | 4.64 | 4.64 |
| 700.59 | 4.12 | 4.12 |