Basic Information
ID: ALA3750621
Type: Binding
Description: Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMP
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: Phosphodiesterase 4(ALA2093863)
Document: ALA3745619
Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMP: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3750621
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 297.32 | 1.89 | 1.89 |
| 267.29 | 1.88 | 1.88 |
| 311.35 | 2.15 | 2.15 |
| 336.18 | 3.19 | 3.19 |
| 375.41 | 1.29 | 1.29 |
| 414.27 | 2.59 | 2.59 |
| 311.35 | 2.14 | 2.14 |
| 437.48 | 2.72 | 2.72 |
| 476.35 | 4.02 | 4.02 |
| 508.56 | 2.42 | 2.42 |
| 547.42 | 3.72 | 3.72 |
| 403.46 | 2.11 | 2.11 |
| 442.33 | 3.41 | 3.41 |
| 408.31 | 4.10 | 4.10 |
| 401.45 | 1.48 | 1.48 |
| 440.31 | 2.78 | 2.78 |