ID: ALA3750816
Type: Binding
Description: Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counter
Organism: Homo sapiens
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA3750816
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
244.25 | 2.02 | 2.02 |
260.32 | 2.73 | 2.73 |
260.32 | 2.73 | 2.73 |
260.32 | 2.73 | 2.73 |
259.33 | 3.33 | 3.33 |
260.32 | 2.73 | 2.73 |
279.32 | 2.12 | 2.12 |
284.34 | 3.21 | 3.21 |
274.35 | 2.92 | 2.92 |
275.33 | 3.04 | 3.04 |
289.36 | 3.34 | 3.34 |
312.39 | 3.79 | 3.79 |
289.36 | 2.83 | 2.83 |
314.37 | 3.24 | 3.24 |
333.41 | 3.36 | 3.36 |
303.38 | 3.48 | 3.48 |
319.38 | 2.71 | 2.71 |
346.41 | 2.46 | 2.46 |
316.38 | 3.29 | 3.29 |
342.42 | 3.68 | 3.68 |
277.32 | 3.47 | 3.47 |
273.36 | 3.64 | 3.64 |
327.33 | 4.35 | 4.35 |
299.40 | 4.21 | 4.21 |
338.23 | 4.10 | 4.10 |
338.23 | 4.10 | 4.10 |
324.20 | 3.71 | 3.71 |
352.25 | 4.49 | 4.49 |
283.35 | 3.81 | 3.81 |
403.43 | 6.02 | 6.02 |
403.43 | 6.02 | 6.02 |
403.43 | 6.02 | 6.02 |
353.42 | 5.14 | 5.14 |
353.42 | 5.14 | 5.14 |
353.42 | 5.14 | 5.14 |