Basic Information
ID: ALA3751565
Type: Binding
Description: Agonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as potentiation of PNU-120596-induced PAM-sensitive desensitization at 30 uM by two-electrode voltage clamp electrophysiology relative to acetylcholine
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA3745606
Agonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as potentiation of PNU-120596-induced PAM-sensitive desensitization at 30 uM by two-electrode voltage clamp electrophysiology relative to acetylcholine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3751565
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.74 | 2.48 | 2.48 |
| 258.29 | 2.85 | 2.85 |
| 269.19 | 2.59 | 2.59 |
| 208.28 | 1.97 | 1.97 |
| 360.28 | 2.67 | 2.67 |
| 376.28 | 2.37 | 2.37 |
| 360.28 | 2.67 | 2.67 |
| 380.70 | 3.02 | 3.02 |
| 376.28 | 2.37 | 2.37 |
| 371.27 | 2.23 | 2.23 |
| 406.31 | 2.38 | 2.38 |
| 414.25 | 3.38 | 3.38 |
| 414.25 | 3.38 | 3.38 |
| 425.15 | 3.13 | 3.13 |
| 425.15 | 3.13 | 3.13 |
| 364.25 | 2.50 | 2.50 |
| 364.25 | 2.50 | 2.50 |
| 389.28 | 1.46 | 1.46 |
| 389.28 | 1.46 | 1.46 |
| 360.28 | 3.12 | 3.12 |
| 357.28 | 3.72 | 3.72 |
| 346.26 | 2.36 | 2.36 |