Basic Information
ID: ALA3751566
Type: Binding
Description: Partial agonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as potentiation of PNU-120596-induced PAM-sensitive desensitization at 30 uM by two-electrode voltage clamp electrophysiology relative to acetylcholine
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA3745606
Partial agonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as potentiation of PNU-120596-induced PAM-sensitive desensitization at 30 uM by two-electrode voltage clamp electrophysiology relative to acetylcholine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3751566
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.27 | 2.23 | 2.23 |
| 380.70 | 3.02 | 3.02 |
| 360.28 | 2.67 | 2.67 |
| 380.70 | 3.02 | 3.02 |
| 362.26 | 2.07 | 2.07 |
| 396.32 | 3.52 | 3.52 |