Basic Information
ID: ALA3754939
Type: Functional
Description: Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-stimulated cAMP production after 1 hr by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Prostanoid EP4 receptor(ALA1836)
Document: ALA3751833
Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-stimulated cAMP production after 1 hr by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3754939
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 682.63 | 7.18 | 7.18 |
| 425.48 | 5.57 | 5.57 |
| 429.90 | 6.73 | 6.73 |
| 389.45 | 4.72 | 4.72 |
| 393.41 | 4.55 | 4.55 |
| 389.45 | 4.72 | 4.72 |
| 393.41 | 4.55 | 4.55 |
| 390.44 | 4.12 | 4.12 |
| 444.41 | 4.83 | 4.83 |
| 390.44 | 4.12 | 4.12 |
| 444.41 | 4.83 | 4.83 |
| 394.86 | 5.28 | 5.28 |