Assay Report Card

Basic Information

ID: ALA3755831

Type: Functional

Description: Antitumor activity against human D54MG cells expressing Escherichia coli PNP M64V mutant xenografted in nude mouse assessed as inhibition of tumor growth at 10 and 20 mg/kg, administered via peritoneal cavity 5 times a day (every 2 hrs) for 3 consecutive days measured on day 17 to 19 after tumor implantation

Organism: Homo sapiens

Cell type: D54MG

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
280.28-0.87-0.87