Basic Information
ID: ALA3755968
Type: Binding
Description: Inhibition of EGF-stimulated EGFR T790M mutant phosphorylation in human H1975 cells assessed as suppression of AKT phosphorylation at 0.3 to 30 nM preincubated for 2 hrs followed by EGF stimulation measured after 15 mins by Western blot analysis relative to WZ4002
Organism: Homo sapiens
Cell type: H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA3755968
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 525.61 | 3.72 | 3.72 |