Assay Report Card

Basic Information

ID: ALA3755971

Type: ADME

Description: Inhibition of EGF-stimulated wild type EGFR phosphorylation in human A431 cells assessed as suppression of AKT phosphorylation at 100 nM preincubated for 2 hrs followed by EGF stimulation measured after 15 mins by Western blot analysis

Organism: Homo sapiens

Cell type: A-431

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
525.613.723.72