Basic Information
ID: ALA3755983
Type: ADME
Description: Prodrug activation in human D54MG cells expressing Escherichia coli PNP M64V mutant xenografted in nude mouse assessed as Escherichia coli PNP M64V mutant-mediated compound cleavage per mg of tumor tissue at 5-20 mg/kg administered via peritoneal cavity 5 times a day (every 2 hrs) for 3 consecutive days measured on day 17
Organism: Escherichia coli
Cell type: D54MG
Activity Charts
Bioactivity
Activity Types for Assay ALA3755983
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.28 | -0.87 | -0.87 |