Basic Information
ID: ALA3756437
Type: Binding
Description: Inhibition of recombinant perforin (unknown origin) mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubation with Jurkat cells at 37 degC for 4 hrs assessed as 51Cr release by gamma counting analysis
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA3756437
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.36 | 4.75 | 4.75 |
| 306.39 | 5.06 | 5.06 |
| 306.39 | 5.06 | 5.06 |
| 306.39 | 5.06 | 5.06 |
| 326.80 | 5.41 | 5.41 |
| 326.80 | 5.41 | 5.41 |
| 326.80 | 5.41 | 5.41 |
| 322.39 | 4.76 | 4.76 |
| 322.39 | 4.76 | 4.76 |
| 322.39 | 4.76 | 4.76 |
| 307.37 | 4.33 | 4.33 |
| 307.37 | 4.33 | 4.33 |
| 308.36 | 4.46 | 4.46 |
| 308.36 | 4.46 | 4.46 |
| 317.37 | 4.62 | 4.62 |
| 317.37 | 4.62 | 4.62 |
| 335.38 | 3.85 | 3.85 |
| 335.38 | 3.85 | 3.85 |
| 334.40 | 3.42 | 3.42 |
| 348.43 | 3.77 | 3.77 |
| 349.41 | 4.11 | 4.11 |
| 363.44 | 4.45 | 4.45 |
| 418.52 | 4.14 | 4.14 |
| 420.53 | 4.43 | 4.43 |
| 364.42 | 4.93 | 4.93 |
| 380.42 | 4.63 | 4.63 |
| 351.38 | 4.03 | 4.03 |
| 351.38 | 3.56 | 3.56 |
| 464.54 | 3.52 | 3.52 |
| 422.51 | 3.75 | 3.75 |
| 395.44 | 3.18 | 3.18 |
| 409.46 | 3.57 | 3.57 |
| 408.44 | 2.67 | 2.67 |
| 422.46 | 3.06 | 3.06 |
| 350.40 | 3.43 | 3.43 |
| 463.56 | 3.40 | 3.40 |
| 421.52 | 3.63 | 3.63 |
| 338.45 | 5.47 | 5.47 |
| 322.39 | 4.24 | 4.24 |
| 370.45 | 4.16 | 4.16 |
| 371.44 | 3.40 | 3.40 |
| 427.55 | 4.83 | 4.83 |
| 385.47 | 4.12 | 4.12 |
| 336.37 | 3.25 | 3.25 |
| 293.35 | 4.15 | 4.15 |
| 348.38 | 4.42 | 4.42 |