Basic Information
ID: ALA3757642
Type: Binding
Description: Inhibition of PGES-1 in IL-1beta stimulated human A549 cell microsomes using PGH2 as substrate assessed as suppression of PGE2 formation at 10 uM preincubated for 15 mins followed by substrate addition by reversed phase-HPLC analysis
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA3757642
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 386.36 | 2.38 | 2.38 |
| 442.56 | 8.11 | 8.11 |
| 450.53 | 6.85 | 6.85 |
| 510.59 | 6.86 | 6.86 |
| 630.69 | 6.90 | 6.90 |
| 414.41 | 3.16 | 3.16 |
| 470.52 | 4.72 | 4.72 |
| 566.61 | 5.61 | 5.61 |