Basic Information
ID: ALA3760365
Type: Functional
Description: Negative allosteric modulator activity at CB1R in mouse brain membranes assessed as Emax for CP55,940-induced [35S]GTPgammaS binding at 1 uM preincubated for 60 mins prior to [35S]GTPgammaS addition by liquid scintillation spectrometric analysis relative to control (Rvb = 94.3%)
Organism: Mus musculus
Tissue: Brain
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA3760365
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.96 | 5.35 | 5.35 |
| 432.59 | 5.43 | 5.43 |