Basic Information
ID: ALA3760805
Type: Binding
Description: Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 mins followed by substrate addition by HPLC-MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3760805
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 230.35 | 2.13 | 2.13 |
| 268.36 | 3.13 | 3.13 |
| 345.45 | 4.19 | 4.19 |
| 369.47 | 4.67 | 4.67 |
| 373.50 | 4.81 | 4.81 |
| 503.24 | 5.71 | 5.71 |
| 395.47 | 3.93 | 3.93 |
| 449.35 | 4.82 | 4.82 |
| 449.35 | 4.82 | 4.82 |
| 344.46 | 4.79 | 4.79 |
| 394.48 | 4.54 | 4.54 |
| 387.46 | 4.80 | 4.80 |
| 405.45 | 4.94 | 4.94 |
| 405.45 | 4.94 | 4.94 |
| 437.47 | 5.68 | 5.68 |
| 383.50 | 4.97 | 4.97 |
| 383.50 | 4.97 | 4.97 |
| 397.52 | 5.23 | 5.23 |
| 411.55 | 5.79 | 5.79 |
| 399.49 | 4.67 | 4.67 |
| 453.46 | 5.56 | 5.56 |
| 370.46 | 4.06 | 4.06 |
| 370.46 | 4.06 | 4.06 |
| 388.45 | 4.20 | 4.20 |
| 384.48 | 4.37 | 4.37 |
| 375.50 | 4.73 | 4.73 |
| 382.51 | 5.08 | 5.08 |
| 402.49 | 4.80 | 4.80 |
| 388.51 | 4.59 | 4.59 |
| 441.58 | 4.99 | 4.99 |
| 469.63 | 5.73 | 5.73 |
| 471.60 | 4.57 | 4.57 |
| 470.62 | 4.15 | 4.15 |
| 415.58 | 5.21 | 5.21 |
| 455.65 | 6.09 | 6.09 |
| 457.62 | 4.93 | 4.93 |
| 456.63 | 4.51 | 4.51 |
| 401.49 | 5.11 | 5.11 |
| 401.49 | 5.11 | 5.11 |
| 382.51 | 5.58 | 5.58 |
| 383.50 | 4.97 | 4.97 |
| 382.51 | 5.01 | 5.01 |
| 286.33 | 4.30 | 4.30 |
| 376.46 | 6.17 | 6.17 |