Basic Information
ID: ALA3761675
Type: Binding
Description: Inhibition of mPGES1 in LPS-induced human whole blood assessed as suppression of PGE2 response after 20 to 24 hrs by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3761675
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.82 | 5.93 | 5.93 |
| 379.26 | 3.09 | 3.09 |
| 320.78 | 2.59 | 2.59 |
| 334.81 | 2.98 | 2.98 |
| 495.45 | 5.26 | 5.26 |
| 548.03 | 8.78 | 8.78 |
| 446.89 | 5.19 | 5.19 |
| 447.87 | 4.59 | 4.59 |
| 461.90 | 4.90 | 4.90 |
| 481.43 | 5.02 | 5.02 |
| 467.40 | 4.62 | 4.62 |
| 336.34 | 2.87 | 2.87 |
| 350.37 | 3.26 | 3.26 |
| 350.37 | 3.26 | 3.26 |
| 368.36 | 3.34 | 3.34 |
| 314.39 | 2.63 | 2.63 |
| 348.83 | 3.37 | 3.37 |
| 334.81 | 2.90 | 2.90 |
| 338.77 | 2.73 | 2.73 |