Basic Information
ID: ALA3766228
Type: ADME
Description: Prodrug activation in human PT37 cells assessed as intracellular cysteamine-CMQT formation at 20 uM incubated for 2 to 24 hrs by HPLC analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PT37
Target: ADMET(ALA612558)
Document: ALA3763053
Prodrug activation in human PT37 cells assessed as intracellular cysteamine-CMQT formation at 20 uM incubated for 2 to 24 hrs by HPLC analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3766228
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.89 | 1.35 | 1.35 |
| 354.90 | 1.08 | 1.08 |
| 150.07 | -0.13 | -0.13 |
| 312.82 | 0.05 | 0.05 |
| 326.85 | 0.44 | 0.44 |
| 340.87 | 0.83 | 0.83 |