Assay Report Card

Basic Information

ID: ALA3766312

Type: ADME

Description: Ratio of drug level in cerebro spinal fluid required to cause reduction of spontaneous activity in po dosed PCP/MK801 stimulated Sprague-Dawley rat hyperlocomotion model to EC50 for positive allosteric modulation of recombinant human mGluR2 by FLIPR assay

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
367.493.983.98