Basic Information
ID: ALA3766329
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis pantothenate synthetase using pantoic acid as substrate and beta-alanine as reactant assessed as NAD+ formation by spectrophotmetry in presence of NADH
Format: BAO_0000357
Organism: Mycobacterium tuberculosis
Target: Pantothenate synthetase(ALA6069)
Document: ALA3763117
Inhibition of Mycobacterium tuberculosis pantothenate synthetase using pantoic acid as substrate and beta-alanine as reactant assessed as NAD+ formation by spectrophotmetry in presence of NADH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3766329
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 137.14 | -0.31 | -0.31 |
| 204.31 | -0.29 | -0.29 |
| 300.34 | 1.78 | 1.78 |
| 314.37 | 2.09 | 2.09 |
| 392.44 | 3.57 | 3.57 |
| 350.40 | 2.93 | 2.93 |
| 306.39 | 2.05 | 2.05 |
| 350.40 | 2.93 | 2.93 |
| 364.43 | 3.24 | 3.24 |
| 442.50 | 4.72 | 4.72 |
| 400.46 | 4.09 | 4.09 |
| 356.45 | 3.20 | 3.20 |
| 363.24 | 3.23 | 3.23 |
| 352.34 | 3.49 | 3.49 |
| 284.34 | 2.47 | 2.47 |
| 374.42 | 2.49 | 2.49 |
| 327.41 | 2.53 | 2.53 |
| 413.30 | 4.38 | 4.38 |
| 402.40 | 4.64 | 4.64 |
| 334.40 | 3.62 | 3.62 |
| 424.48 | 3.65 | 3.65 |
| 377.47 | 3.69 | 3.69 |
| 336.21 | 3.72 | 3.72 |
| 257.32 | 2.96 | 2.96 |
| 287.34 | 2.97 | 2.97 |
| 271.35 | 2.63 | 2.63 |
| 263.37 | 2.77 | 2.77 |
| 386.27 | 4.87 | 4.87 |
| 307.38 | 4.11 | 4.11 |
| 351.43 | 4.51 | 4.51 |
| 321.41 | 3.79 | 3.79 |
| 313.43 | 3.92 | 3.92 |