Basic Information
ID: ALA3766467
Type: Binding
Description: Agonist activity at human alpha7 receptor expressed in mouse Neuro2a cells assessed as induction of intracellular calcium level preincubated with PNU-120596 for 20 mins followed by compound addition measured every 2 sec for 3 mins by fluorescence microplate reader analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Neuro2a
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA3763033
Agonist activity at human alpha7 receptor expressed in mouse Neuro2a cells assessed as induction of intracellular calcium level preincubated with PNU-120596 for 20 mins followed by compound addition measured every 2 sec for 3 mins by fluorescence microplate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3766467
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.81 | 2.52 | 2.52 |
| 289.81 | 2.52 | 2.52 |
| 289.81 | 2.52 | 2.52 |
| 317.82 | 2.06 | 2.06 |