Basic Information
ID: ALA3766477
Type: Binding
Description: Inhibition of recombinant human TYK2 kinase domain (885-1176 residues) using Ulight-JAK1 substrate peptide assessed as reduction in ATP-dependent substrate phosphorylation after 45 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3766477
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 243.70 | 3.47 | 3.47 |
| 371.43 | 1.10 | 1.10 |
| 385.84 | 4.11 | 4.11 |
| 260.68 | 1.95 | 1.95 |
| 340.77 | 2.35 | 2.35 |
| 337.77 | 3.01 | 3.01 |
| 316.36 | 3.27 | 3.27 |
| 320.36 | 2.00 | 2.00 |
| 300.37 | 1.92 | 1.92 |
| 286.34 | 1.68 | 1.68 |
| 286.34 | 1.36 | 1.36 |
| 314.39 | 2.31 | 2.31 |
| 382.47 | 2.42 | 2.42 |
| 382.47 | 2.42 | 2.42 |
| 382.47 | 2.42 | 2.42 |
| 300.37 | 1.92 | 1.92 |
| 385.47 | 1.76 | 1.76 |
| 384.48 | 2.82 | 2.82 |
| 433.54 | 1.16 | 1.16 |
| 358.45 | 2.15 | 2.15 |