Basic Information
ID: ALA3766667
Type: Binding
Description: Inhibition of JAK1/JAK2/TYK2 in human PBMC assessed as reduction in IL-6-induced STAT1 phosphorylation preincubated for 5 mins followed by IL-6 stimulation for 15 to 60 mins by flow cytometry analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3766667
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.43 | 1.10 | 1.10 |
| 358.45 | 2.15 | 2.15 |