Basic Information
ID: ALA3767150
Type: Binding
Description: Inhibition of IKKbeta (unknown origin) transfected in human HeLa cells assessed as inhibition of TPA-induced NF-kappaB activation at 10 uM pre-incubated with compound for 1 hr followed by TPA addition after 8 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA3767150
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.76 | 5.00 | 5.00 |
| 616.81 | 5.60 | 5.60 |
| 570.74 | 5.77 | 5.77 |
| 575.76 | 5.91 | 5.91 |
| 559.76 | 6.21 | 6.21 |
| 563.72 | 6.04 | 6.04 |
| 580.18 | 6.55 | 6.55 |
| 624.63 | 6.66 | 6.66 |
| 623.82 | 5.30 | 5.30 |
| 590.73 | 5.81 | 5.81 |
| 560.75 | 5.48 | 5.48 |
| 602.78 | 5.86 | 5.86 |
| 638.84 | 5.27 | 5.27 |